Innovating Works

EMbRACe

Financiado
Effective Multidrug Cocktails for Cancer
Cancer is a global epidemic that affects all ages and socio-economic groups. In turn, tremendous resources are being invested in prevention, diagnosis, and treatment of cancer. For instance, over 1,000 anticancer drugs are current... Cancer is a global epidemic that affects all ages and socio-economic groups. In turn, tremendous resources are being invested in prevention, diagnosis, and treatment of cancer. For instance, over 1,000 anticancer drugs are currently in various phases of development and pre-approval testing, more than the number for heart disease, stroke, and mental illness combined. Finding multi-drug combinations for cancer is an increasingly pressing therapeutic challenge. However, screening all possible drug combinations is an impossible task because the number of experiments grows exponentially with the number of different drugs and doses. Therefore, highly effective combinations of already approved drugs may likely exist that have never been tested before at the appropriate doses, due the astronomical number of wet lab tests required to find these combinations. Motivated by this challenge, we have developed a novel method for computing the effects of high order combinations of drugs on cancer cells and predicting the best drug for a given tumor based only on a very small number of experiments. In turn, the goals of our PoC project are to further validate the potential of our formula by means of numerous rigorous tests and to establish the business potential of our idea. If successful, this PoC project will pave the way to the development and adoption of highly personalized drug cocktails that are designed based only on a limited number of measurements performed on patient-derived tumor material. ver más
30/04/2018
WEIZMANN
150K€
Duración del proyecto: 18 meses Fecha Inicio: 2016-10-18
Fecha Fin: 2018-04-30

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2018-04-30
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-PoC-2015: ERC Proof of Concept Grant
Cerrada hace 9 años
Presupuesto El presupuesto total del proyecto asciende a 150K€
Líder del proyecto
WEIZMANN INSTITUTE OF SCIENCE No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5