SUMOMyePath
Financiado
UNVEILING THE ROLE OF SUMOYLATION AS NOVEL MOLECULAR PATHWAY IN MYELIN BIOLOGY;...
UNVEILING THE ROLE OF SUMOYLATION AS NOVEL MOLECULAR PATHWAY IN MYELIN BIOLOGY; IMPLICATION IN NEURODEVELOPMENT AND DEMYELINATING PATHOPHYSIOLOGY.
SUMOMyePath: a New Pathway to Wrestle Demyelinating diseases.(Re)myelination is the process by which Oligodendrocyte Precursor Cells (OPCs) migrate and differentiate and mature into myelin generating Oligodendrocytes (OLs). Under...
SUMOMyePath: a New Pathway to Wrestle Demyelinating diseases.(Re)myelination is the process by which Oligodendrocyte Precursor Cells (OPCs) migrate and differentiate and mature into myelin generating Oligodendrocytes (OLs). Understanding this process is key to cure demyelinating disorders of which, Multiple Sclerosis (MS), is the most prevalent, affecting 2.8 million individuals worldwide and specially women (69%). SUMOylation is a post-translational modification mainly studied in neurons within the central nervous system, however its pathway’s role in oligodendroglia and its relation with myelin (patho)physiology remains to be investigated. Thus, it is an exciting field to explore and SUMOMyePath will address this challenge by synergizing the applicant’s experience in SUMOylation and myelin biology and the expertise of 1) the host group´s (UniTo) in OPCs biology and 2) the secondment group´s (Ubx) in state-of-art live-imaging of OL lineage cells, opening novel avenues of research and, as consequence, new diagnostic and therapeutic strategies.
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Duración del proyecto: 23 meses
Fecha Inicio: 2024-04-01
Fecha Fin: 2026-03-31
Fecha Fin: 2026-03-31
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-04-01
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2022-PF-01-01:
MSCA Postdoctoral Fellowships 2022
Cerrada
hace 2 años
Líder del proyecto
UNIVERSITA DEGLI STUDI DI TORINO
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5