Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

NO-MND

Financiado

Cerrado

Transferring NOn autonomous cell degeneration models between EU and USA for deve...

Transferring NOn autonomous cell degeneration models between EU and USA for development of effective therapies for Motor Neuron Diseases MND "Amyotrophic lateral sclerosis (ALS) and Spinal Muscular Atrophy (SMA) are fatal diseases characterized by selective degeneration of motor neurons without any effective treatment. Non-neuronal cells like astrocytes play a key role... ver más

31/01/2018

UMIL

376K€

Presupuesto del proyecto: 376K€

Líder del proyecto

UNIVERSITA DEGLI STUDI DI MILANO No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 2 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2018-01-31 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

UMIL

0.00€ | Lider

BIOMEDICAL RESEARCH FOUNDATI...

N.D. | Participante

Proyectos interesantes

ExItALS

Medical Technol...

Data Science

180K€ Cerrado

TOXICITY IN MND

Medical Technol...

Applied Physics

272K€ Cerrado

Neurovulnerability

Medical Technol...

Applied Physics

1M€ Cerrado

SAF2012-31831

Medical Technol...

Data Science

70K€ Cerrado

muscleTDP

Medical Technol...

Applied Physics

203K€ Cerrado

NOVEL ALS MODELS

Medical Technol...

Data Science

100K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Líder del proyecto

UNIVERSITA DEGLI STUDI DI MILANO No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 376K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto "Amyotrophic lateral sclerosis (ALS) and Spinal Muscular Atrophy (SMA) are fatal diseases characterized by selective degeneration of motor neurons without any effective treatment. Non-neuronal cells like astrocytes play a key role in the pathogenesis of ALS and SMA. Understanding the mechanisms of cell death caused by non-neuronal cells is a major research target and it has been proposed that transplantation of non-neuronal cells can represent a new therapeutic strategy for these disorders. The proposed NO-MND project addresses scientific issues related to non autonomous cell death in motor neuron disorders, by strengthening research partnerships through staff exchanges and networking activities between 2 European research organizations from Italy, Greece and 1 organization from the USA. The program is focused on: 1) development of in vitro disease models to investigate molecular interactions between non-neuronal cells and motor neurons using cell reprogramming technology; 2) investigation of potential therapeutic efficacy of non-neuronal cells transplantation in motor neuron disease models. The project is based on a 4 year coordinated joint program of exchange of researchers. The three groups have a long standing experience in motor neuron disease field, in cellular and in vivo models, non cell autonomous diseases mechanism and cell replacement therapy. Their ongoing research is supported by multiple grants. Four topics have been identified as most relevant for all partners involved in the joint program: Astrocytes reprogrammed from fibroblasts of ALS (1) and SMA (2) patients in a cellular model to study the pathogeneses of these diseases and their use in therapeutic approaches for ALS (3) and SMA (4) using in vivo models. The IRSES scheme provides a unique opportunity to integrate past collaboration activities into a coherent program addressing an issue of high priority for public health agendas of the EU and USA."

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores