Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

CryoET-CryoCloud

Financiado

Streamlining structural biology: Developing a high-throughput cloud-based cryo-e...

Streamlining structural biology: Developing a high-throughput cloud-based cryo-electron tomography platform Cryo-electron microscopy (cryoEM) has revolutionized biomolecular research. It enables structure determination of proteins and their complexes at near-atomic resolution, informing on their mechanism of action and their role in dis... ver más

31/12/2024

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

UNIVERSITEIT UTRECHT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-12-31

ERC-2022-POC2: ERC PROOF OF CONCEPT GRANTS2 Objective:Objectives:

I+D

Cerrada hace 2 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

150.00K€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

BES-2016-078854 Computational Biology and Biomedical Systems 93K€ Cerrado

RYC-2015-17519 Structural Bioinformatics in Biological and Clinical Researc... 309K€ Cerrado

EUIN2013-51160 NEW BIOINFORMATICS TOOL TO INTEGRATE, UNDERSTAND AND EXPLOIT... 25K€ Cerrado

RTI2018-094494-B-C22 DISEÑO DE HERRAMIENTAS DE MICROSCOPIA TRIDIMENSIONAL Y PROCE... 129K€ Cerrado

TED2021-132748B-I00 PROCESAMIENTO DIGITAL DE IMAGENES EN CRIOMICROSCOPIA: ROMPIE... 167K€ Cerrado

RYC2020-029099-I Bioengineering Molecular Imaging Tools for Precision Medicin... 324K€ Cerrado

Duración del proyecto: 18 meses Fecha Inicio: 2023-06-19
Fecha Fin: 2024-12-31

Líder del proyecto

UNIVERSITEIT UTRECHT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 150K€

Descripción del proyecto Cryo-electron microscopy (cryoEM) has revolutionized biomolecular research. It enables structure determination of proteins and their complexes at near-atomic resolution, informing on their mechanism of action and their role in disease. Importantly, it also assists the development of novel therapeutics. Cryo-electron tomography (cryoET) is an emerging cryoEM modality, which has demonstrated the potential of to determine protein structures at near-atomic resolution in their near-native environment. Importantly, cryoET provides snapshots of macromolecules during their function, allowing to capture different stages of biochemical reactions in the cell and inferring their temporal order. However, cryoET relies on extensive computational data analysis. Current analysis pipelines require extensive computational resources, various software packages, and a high degree of expertise to build and execute workflows for data analysis. Building on my previous research from the ERC Consolidator project BENDER project, I propose to create a cloud-based workflow for standardized and automated high-throughput cryoET data analysis (CryoET-CryoCloud). This solution will not only reduce analysis time from months to days, but it will also make the method accessible to a broad community by eliminating the need for investment into expensive computational infrastructure, and their maintenance through scarce qualified personnel. My proposed workflow will both enable and democratize high-content data analysis of cellular tomograms, thus dramatically increasing our knowledge of the molecular machinery inside the cell. To perform this work and reach market rapidly, I will perform CryoET-CryoCloud in very close collaboration with a team of people from the startup company CryoCloud, which emerged from my research group.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores