Shedding light on the diversity ecology and evolution of enigmatic uncultivate...
Shedding light on the diversity ecology and evolution of enigmatic uncultivated archaea using novel single cell and metagenomics approaches
The Archaea represent the Third Domain of Life and comprise a group of microorganisms that are important players in major biogeochemical cycles. Yet, even though more than 30 years have passed since their discovery, the biology,...
ver más
¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video
Proyectos interesantes
CTM2017-87736-R
RECONSTRUCCION DE GENOMAS MICROBIANOS MARINOS MEDIANTE METAG...
156K€
Cerrado
DARKCELLS
Single cell phylogenomic exploration of archaeal dark matter
198K€
Cerrado
BIO2008-00082
GENOMICA Y PROTEOMICA PARA EL ESTUDIO DE LA REGULACION DE LA...
133K€
Cerrado
AGL2013-42628-R
ESTUDIO METAGENOMICO Y METATRANSCRIPTOMICO DEL LA MICROBIOTA...
235K€
Cerrado
CTM2015-70340-R
REGULACION DEL (META)GENOMA PROCARIOTICO DE UN AMBIENTE COST...
219K€
Cerrado
BES-2014-068285
EOLOGIA DE LOS MICROORGANISMOS MARINOS: BIODIVERSIDAD, GENOM...
88K€
Cerrado
Información proyecto ENIGMAARCHAEA
Líder del proyecto
UPPSALA UNIVERSITET
No se ha especificado una descripción o un objeto social para esta compañía.
TRL
4-5
Presupuesto del proyecto
198K€
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
The Archaea represent the Third Domain of Life and comprise a group of microorganisms that are important players in major biogeochemical cycles. Yet, even though more than 30 years have passed since their discovery, the biology, lifestyle and diversity of the archaeal domain of life remain to be poorly understood thus far, especially when compared to that of Bacteria and eukaryotes.
Recent environmental surveys have revealed the existence of a vast, uncultured archaeal diversity, and the characterization of this so called archaeal dark matter is of great significance for understanding the diversity, biogeography and ecological relevance of Archaea in general, and the evolution of cellular life on Earth in particular. Yet, efforts to do so have been hampered by difficulties to cultivate these archaeal lineages under laboratory conditions.
The current project aims to employ powerful, cultivation-independent approaches to genomically probe several deeply-branching archaeal lineages in order to set genomic standards for quantifying and defining archaeal taxonomic units, to determine molecular signatures of archaeal genomes, to reveal potential ecological functions of uncultivated archaea and to shed new light on the evolutionary relationship between Archaea and Eukaryotes. By combining state-of-the-art single cell genomics and metagenomics workflows with cutting-edge next-generation sequencing and bioinformatics pipelines, genomic data of several deep archaeal lineages will be generated and analyzed, focusing on the enigmatic Korarchaeota, as well as of representatives of the deeply-rooting Deep Sea Archaeal Group (DSAG) and the Ancient Archaeal Group (AAG). The proposed phylogenomic and comparative genomic analyses of these genomic datasets will reveal important novel insights into the enigmatic archaeal domain of life.