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SMARTCELL

Financiado

Cerrado

Rational design of plant systems for sustainable generation of value added indus...

Rational design of plant systems for sustainable generation of value added industrial products Plants sustainably produce low levels of secondary metabolites of high industrial value. However, they are often too complex to be economically manufactured by chemical synthesis. Advanced metabolic engineering and exploitation of... ver más

30/09/2013

VTT

8M€

Presupuesto del proyecto: 8M€

Líder del proyecto

TEKNOLOGIAN TUTKIMUSKESKUS VTT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 17 Participantes

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2013-09-30 No tenemos la información de la convocatoria

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

17 Participantes

VTT

0.00€ | Lider

PAT

N.D. | Participante

CNRS

N.D. | Participante

ETH Zürich

N.D. | Participante

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Líder del proyecto

TEKNOLOGIAN TUTKIMUSKESKUS VTT No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 8M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Plants sustainably produce low levels of secondary metabolites of high industrial value. However, they are often too complex to be economically manufactured by chemical synthesis. Advanced metabolic engineering and exploitation of plants as Green Factories has been prevented due to poorly understood metabolic pathways in plants and the regulation thereof. SmartCell brings together 14 leading European academic laboratories and four industrial partners in order to create a novel concept for rationally engineering plants towards improved economical production of high-value compounds for non-food industrial use. Although SmartCell focuses on terpenoids, the largest class of secondary metabolites, which exhibit extremely diverse biological and pharmaceutical activities, all knowledge, tools and resources developed in the project, are generic and broadly applicable to engineer any plant biosynthetic pathway. A systems biology approach using metabolomics and transcriptomics is taken to move beyond the state of the art. New multigene transfer technologies are developed. By screening and functionally categorizing genes at structural, regulatory and transport levels a comprehensive knowledge base of how secondary metabolite biosynthetic pathways operate in plants is developed. The case study component i.e. manufacturing a valuable terpenoid in an optimized large-scale system gives SmartCell a unique opportunity to directly make transition from fundamental science to application. For long-term exploitation an integrated database, compound library, cell culture collection and a genebank available for academic and industrial communities will be established. SmartCell provides new opportunities for SMEs and established European biotech companies, and the technology can also be transferred to other e.g. fine chemical and pharmaceutical industries. SmartCell will prove that plant-based resources can furnish the European society and industry far more than they presently do.

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