MAGERY
Financiado
Mechanics-augmented brain surgery
This project aims at revolutionising the treatment of brain disorders through mechanics-augmented brain surgery (MAGERY). Due to the ultrasoft nature of brain tissue, surgical procedures have exceptionally high requirements for mi...
This project aims at revolutionising the treatment of brain disorders through mechanics-augmented brain surgery (MAGERY). Due to the ultrasoft nature of brain tissue, surgical procedures have exceptionally high requirements for minimal invasiveness and maximal safety. During the procedure, brain tissue largely deforms and is easily loaded beyond its functional tolerance. A promising technology to improve surgical outcomes is to integrate virtual information either through immersed virtual reality (VR) in training and planning or through augmented reality (AR) overlaying virtual information with the surgeon’s real view. Despite rapid advances, to date, most VR/AR solutions have disregarded the complex region-dependent mechanical properties of brain tissue and mechanics-induced cell dysfunction or death.
The MAGERY project will follow a new paradigm by focusing on brain mechanics. We imply that we can minimise unnecessary brain tissue damage by integrating continuum mechanics-based simulations into VR/AR solutions. Realising this objective will require to combine state-of-the-art approaches in live cell imaging, nonlinear continuum mechanics, and computational engineering. The applicant and the MAGERY team will for the first time perform simultaneous large-strain mechanical measurements and multiphoton microscopy, and, through modelling and simulations, identify thresholds for tissue and cell damage under complex three-dimensional loadings. By merging simulation results and VR/AR techniques, this project strives towards real-time predictions of brain tissue deformation and corresponding damage. With her pioneering role in testing and modelling the complex behaviour of human brain tissue, the applicant has excellent prerequisites to tackle these challenges.
If successful, this project can not only revolutionise VR/AR for brain surgery, but also leverage our understanding of the cellular response to three-dimensional mechanical loading across length and time scales.
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Duración del proyecto: 71 meses
Fecha Inicio: 2023-10-17
Fecha Fin: 2029-09-30
Fecha Fin: 2029-09-30
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-10-17
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
ERC-2023-STG:
ERC STARTING GRANTS
Cerrada
hace 2 años
Presupuesto
El presupuesto total del proyecto asciende a
2M€
Líder del proyecto
FRIEDRICHALEXANDERUNIVERSITAET ERLANGENNUERNB...
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5