Hola,
¿eres nuevo aquí?

Registrate y conecta tu empresa con financiación pública, partners y proyectos.

PhenoTECH

Financiado

Large scale platform for motion detection and fluorescence imaging in zebrafish...

Large scale platform for motion detection and fluorescence imaging in zebrafish models of neurological disorders The PhenoTECH project aims to develop a novel technology with high-throughput capacity for screening and phenotyping of genetic models of disease. PhenoTECH will enable an unprecedented capability to monitor and control multiple p... ver más

30/09/2022

ASOCIATIA TRANSYLV...

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

ASOCIATIA TRANSYLVANIAN INSTITUTE OF NEUROSCI... No se ha especificado una descripción o un objeto social para esta compañía.

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-09-30

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

ERC-2019-POC: ERC Proof of Concept Grant

I+D

Cerrada hace 5 años

0% 100%

2 Participantes

ASOCIATIA TRANSYLVANIAN INST...

150.00K€ | Lider

ECOFOND

Proyectos interesantes

EIN2020-112381 MODELIZACION DE ENFERMEDADES NEURODEGENERATIVAS 15K€ Cerrado

EQC2018-005332-P Detección precoz de enfermedades neurodegenerativas con inmu... 67K€ Cerrado

SAF2011-22506 ANALISIS DE TRANSCRIPTOMAS EN MODELOS DE ENFERMEDADES NEUROD... 133K€ Cerrado

EQC2018-004897-P EQUIPAMIENTO PARA PLATAFORMA DE FENOTIPADO MURINO 181K€ Cerrado

FLUBIODEM Fluid Biomarkers for Neurodegenerative Dementias 2M€ Cerrado

PID2021-124430OA-I00 ESTUDIO DE LAS DIFERENCIAS DE SEXO EN ENFERMEDADES NEURODEGE... 157K€ Cerrado

Últimas noticias

25-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 52 concesiones

25-11-2024: CMVAMADRID En las últimas 48 horas el Organismo CMVAMADRID ha otorgado 1 concesiones

25-11-2024: FUNDACION-EOI En las últimas 48 horas el Organismo FUNDACION EOI ha otorgado 6 concesiones

Duración del proyecto: 24 meses Fecha Inicio: 2020-09-17
Fecha Fin: 2022-09-30

Presupuesto del proyecto 150K€

Descripción del proyecto The PhenoTECH project aims to develop a novel technology with high-throughput capacity for screening and phenotyping of genetic models of disease. PhenoTECH will enable an unprecedented capability to monitor and control multiple parameters that will significantly contribute to advancing fundamental and biopharmaceutical research, strongly accelerating discovery of novel treatments for debilitating neurodegenerative diseases. PhenoTECH’s immediate impact will be on the ERC Consolidator Grant, ALS-Networks, where we intend to utilize the power of zebrafish for high-throughput functional screens to uncover defective cellular pathways and to identify therapeutic targets for ALS and related neurodegenerative disorders. High-throughput phenotype-based screening efforts have until now been hampered by the lack of technology that would allow for parallel monitoring of behavioral, cellular and physiological markers of disease. To overcome this limitation, PhenoTECH will build an innovative platform for automated phenotypic analysis consisting of three modules: i) custom designed multiwell plates with the capacity for in-well perfusion of solutions, greatly facilitating and optimizing drug delivery, wash-out, temperature and oxygenation control; ii) state of the art motion (motor) tracking with analysis of spontaneous and evoked locomotion of zebrafish larvae; iii) fluorescence detection of genetically-encoded transgenic line reporters to enable live monitoring and imaging of cellular processes and neuronal activity. By combining these three capabilities, PhenoTECH will surpass any existing commercial product on the market and will enable low-cost, large-scale screening capability for development of efficient treatments to neurodegenerative diseases. PhenoTECH will have a strong societal and economic impact by providing a technological leap forward that will boost fundamental and biopharmaceutical research & development.

Conecta tu I+D

Entra hoy

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores