Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

GASTRIC

Financiado

Cerrado

Gastrointestinal Tract on Chip An automated microfluidics based modular device...

Gastrointestinal Tract on Chip An automated microfluidics based modular device for complete simulation of the processes of digestion and absorption of orally ingested bioactive compounds People can only ingest food through the oral cavity, and oral administration remains the preferred route for the delivery of drugs or dietary supplements. However, orally ingested compounds must first survive digestion and then be... ver más

15/10/2022

LABORATORIO IBERIC...

160K€

Presupuesto del proyecto: 160K€

Líder del proyecto

INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATO... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-10-15

WF-02-2019: Widening Fellowships

I+D

Cerrada hace 5 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

LABORATORIO IBERICO INTERNAC...

159.82K€ | Lider

Proyectos interesantes

RTI2018-096786-B-I00

Medical Technol...

Data Science

212K€ Cerrado

EQC2019-006060-P

Medical Technol...

Data Science

214K€ Cerrado

IMBIBE

Medical Technol...

Data Science

2M€ Cerrado

PROMETEO

Medical Technol...

Data Science

Cerrado

SMs-Gut

Medical Technol...

Data Science

175K€ Cerrado

microMAGNETOFLUIDICS

Medical Technol...

Data Science

187K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Duración del proyecto: 24 meses Fecha Inicio: 2020-09-30
Fecha Fin: 2022-10-15

Líder del proyecto

INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATO... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 160K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto People can only ingest food through the oral cavity, and oral administration remains the preferred route for the delivery of drugs or dietary supplements. However, orally ingested compounds must first survive digestion and then be absorbed at the small intestine to reach the systemic circulation. This proposal aims to develop and fabricate the first automated microfluidics-based device for complete simulation of the processes of digestion and intestinal absorption of orally ingested bioactive compounds. The innovation lies on the capacity to simulate the process in full and, on the introduction of integrated sensors for online, real-time monitoring of the pH, barrier integrity, intestinal permeation and cellular responses. In addition, the use of primary cells will allow to create disease models and patient-specific tissues for personalised medicine. Co-cultures with the gut microbiome will allow to assess the effect of the ingested compounds on commensal bacteria and of the latter in nutrient digestion. The work will be conducted at the International Iberian Nanotechnology Laboratory in Portugal, with two secondments projected at the University of Southampton for 4 months, and intersectorally at GlaxoSmithKline, in Stevenage, UK for 2 months. The device will offer the possibility to study minute sample amounts, with high resolution and with the potential for high-throughput analysis, which is key for its adoption by large pharmaceutical and food industries with high economic and social impact. The proposal aligns with the societal challenges 1 (Health, demographic change and wellbeing) and 2 (Food security) of the current Horizon 2020 work programme. The work is multidisciplinary and the combination of learning through research and a comprehensive training plan will strongly improve the applicant's researcher profile and career prospects.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores