DrugCer
Financiado
Cold Sintering Process for Fabrication of Biodegradable Drug-Eluting Ceramics
DrugCer proposes a paradigm shift in drug delivery for bone restoration by making drugs an inherent part of a biodegradable ceramic implant. Such a new approach would require drug loading during ceramic sintering, which in turn re...
DrugCer proposes a paradigm shift in drug delivery for bone restoration by making drugs an inherent part of a biodegradable ceramic implant. Such a new approach would require drug loading during ceramic sintering, which in turn requires multidisciplinary research and development of low-temperature/cold ceramic processing. Accordingly, the main research goal of DrugCer is to apply a novel pressure-assisted Cold Sintering Process (CSP) for co-sintering of biodegradable ceramics with drugs. To achieve the goal, the researcher will receive advanced training in CSP and develop the co-sintering process by establishing a relationship between the processing parameters and properties of the resulting bioceramics. She will train in and master cryo-focused ion beam milling and cryo-scanning transmission electron microscopy to investigate the process kinetics and densification mechanisms. Finally, she will train in and develop methods for complex shaping to adapt the method for potential translation to preclinical studies. Cold-sintering will decrease energy consumption in bioceramics’ fabrication. It will also enable bioceramic co-sintering with other temperature-sensitive materials (e.g., polymers), opening paths to innovations in fields beyond orthopedics or even medicine (e.g., construction ceramics).
Multidisciplinary supervising teams at Fraunhofer IKTS (host) and Penn State University (secondment) will support training through research and transferrable skills development (grant writing, teaching/mentoring, project management, networking, and horizontal skills). Inter-sectoral communication with Charité hospital (short visits) will ensure high-quality guidance in developing prospective biomedical technology from its very beginning. Thus, DrugCer will equip the researcher with unique expertise, skills, and a professional network for establishing an independent group in the niche of low-temperature, energy-efficient ceramic processing.
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Duración del proyecto: 35 meses
Fecha Inicio: 2022-08-09
Fecha Fin: 2025-07-31
Fecha Fin: 2025-07-31
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-08-09
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2021-PF-01-01:
MSCA Postdoctoral Fellowships 2021
Cerrada
hace 3 años
Presupuesto
El presupuesto total del proyecto asciende a
174K€
Líder del proyecto
FRAUNHOFER GESELLSCHAFT ZUR FORDERUNG DER ANG...
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
N.D. |
Participante