Innovating Works

iaFRET

Financiado
An amplified signal imaging software for prognosis of cancer enabling the evalua...
An amplified signal imaging software for prognosis of cancer enabling the evaluation of clinicalefficiency of personalised cancer treatments to an unprecedented level. Chemotherapy remains the main treatment in locally advanced or metastatic lung cancer. The wide use of chemotherapiesis often lengthy (4 months) and is not supported by any patient stratification tools, leading to life-threatening... Chemotherapy remains the main treatment in locally advanced or metastatic lung cancer. The wide use of chemotherapiesis often lengthy (4 months) and is not supported by any patient stratification tools, leading to life-threatening risk. currenttechniques used to identify biomarkers for target or immunotherapy (i.e. Immunohistochemistry and Protein Ligase Assays)lack of sensitivity (up to 30% of false negatives) resulting in qualitative, subjective measurements with poor prognostic value.iaFRET is an imaging system based on a proprietary time resolved Amplified Forester Resonance Energy Transfer (FRET)technique. It determines both molecular and cell-cell interactions, enabling the evaluation of clinical efficiency ofpersonalised cancer treatments. iaFRET enables oncologists to define the most effective treatment for cancer case andverify its efficacy anytime during the therapy. FASTBASE will need to finalise the engineering of the machine, optimize theimage analysis algorithms and user interface, conduct a clinical trial to demonstrate and validate the safety, efficacy and costsavings of technology. Globally there are almost 300 research institutes and hospitals currently working on cancer researchworldwide, 147 in EU. Emerging frontiers like immunotherapy highly require technology like iaFRET. iaFRET can contributeto European health system by improving the prognosis and treatment selection for cancer patients, hence increasing the lifeexpectancy of patients affected by this pathology. ver más
30/04/2018
71K€
Duración del proyecto: 2 meses Fecha Inicio: 2018-02-01
Fecha Fin: 2018-04-30

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2018-04-30
Presupuesto El presupuesto total del proyecto asciende a 71K€
Líder del proyecto
FASTBASE SOLUTIONS El desarrollo, asesoramiento y comercializacion de productos y servicios para la investigacion
Perfil tecnológico TRL 4-5 1M