A potent Micro RNA therapeutic for nonalcoholic fatty liver disease NAFLD
Fatty Liver disease (FLD) is a widespread disease which can often progress to Nonalcoholic steatohepatitis, cirrhosis and liver cancer. At present FLD disease affects a huge perportion of the population and prompt treatment will b...
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Información proyecto FLDcure
Duración del proyecto: 18 meses
Fecha Inicio: 2014-12-11
Fecha Fin: 2016-06-30
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
Fatty Liver disease (FLD) is a widespread disease which can often progress to Nonalcoholic steatohepatitis, cirrhosis and liver cancer. At present FLD disease affects a huge perportion of the population and prompt treatment will be of major health benefits to the general population. We have developed a specific therapeutic targeting a microRNA we and others have shown to be involved in the pathogenesis of FLD. This therapeutic agent can dramatically reduce FLD in a mouse model. We would like to extend the pre-clinical studies in order to encourage interest of a pharmaceutical company who will license the technology and pursue clinical trials.