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FRESCO4NoPain: Frontier RESearch COmpetences for Neuro modulation and Oscillations in Pain National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs participó en un HORIZON EUROPE: HORIZON-MSCA-2023-DN-01 Chronic pain is a major societal and economic European burden, affects one in five adults, and its inadequate relief indicates a major unmet...
2024-06-26 - 2029-01-31 | Financiado

EPAD: European Prevention of Alzheimer’s Dementia Consortium National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs participó en un FP6: Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression...
2015-01-01 - 2019-12-31 | Financiado

THINGS2D0: THINGS2DO National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs participó en un FP6: The program THINGS2DO is focused on building the Design & Development Ecosystem for FD-SOI-technology. This technology is uniquely...
2014-01-01 - 2018-01-01 | Financiado

EMIF: European Medical Information Framework National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs participó en un FP6: In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected,...
2013-01-01 - 2018-06-30 | Financiado

STEMBANCC: Stem cells for Biological Assays of Novel drugs and prediCtive toxiCology (StemBANCC) National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs participó en un FP6: StemBANCC, comprising internationally renowned investigators, is ideally positioned to deliver a unique European biorepository and drug disc...
2012-10-01 - 2018-03-31 | Financiado

ACMO: Systematic dissection of molecular machines and neural circuits coordinating C. elegans aggregation... National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: Elucidating how neural circuits coordinate behaviour, and how molecules underpin the properties of individual neurons are major goals of neu...
Financiado

SENSENET: International sensor development network National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: This ITN project will train young investigators to enable them make significant advances in the field of in situ sensor technology. It will...
Financiado

MIDAS: Millimetre wave Integrated Diode and Amplifier Sources National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: The MIDAS project will redress the technology imbalance between the EU and the US in a most significant area of European technology non-depe...
Financiado

ROBIN: Role Of Biodiversity In climate change mitigatioN National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: To realise the full potential of tropical forests in climate change mitigation (CCM) & the provision of other ecosystem services in the face...
Financiado

INSTINCTIVE DRIVES: Orchestration of instinctive drives National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: A major goal of 21st century science is to protect human health from the growing mismatch between ancient behavioural instincts and modern s...
Financiado

MICRORNA EXPORT: Structural and biophysical mechanism of microRNA nuclear export National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: MicroRNAs are a recently discovered class of small non-coding RNAs that act as post-transcriptional regulators of gene expression by silenci...
Financiado

STRUCTUREU4U6SNRNP: Structural and Biochemical Examination of the Yeast U4 U6 snRNP. National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: The spliceosome is a large RNA–protein assembly that catalyzes the removal of introns from mRNA precursors (pre-mRNA) and the splicing of co...
Financiado

NEURORNATRANSPORT: Molecular mechanims of mRNA transport in neurons National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: RNA transport coupled to local translation presents an efficient means to regulate gene expression in time and space. Recent studies have in...
Financiado

ADAR1 AND RNAI: Understanding the mechanism behind ADAR1 Adenosine DeAminase acting on RNA 1 modulation of the RNA... National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: The most common form of editing in mammalian RNA is deamination of adenosine to inosine by ADAR1 and ADAR2. ADAR1p150, an interferon inducib...
Financiado

MIRNA BIOGENESIS: Auxiliary factors involved in the post transcriptional regulation of microRNA expression. National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: MicroRNAs (miRNAs) are small non-coding RNAs that negatively regulate gene expression of complementary mRNAs. They have diverse unique expre...
Financiado

MIRNASTRESS: miRNASTRESS structural and functional study of the RBM38 controlled mechanism of mRNA stabilization... National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: The aim of the research activities detailed in this proposal is to understand how the RNA-binding protein RBM38 mediates the cellular stress...
Financiado

PATTERN AND GROWTH: Coordination of patterning and growth in the developing neural tube National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: Developing organs are patterned as they grow, but it is poorly understood how patterning and growth are coordinated to produce tissues of co...
Financiado

TEMPINTSHH: Temporal regulation by Sonic Hedgehog of neural progenitor identity during vertebrate neurogenesis. National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: The central nervous system (CNS) is the most complex organ in the vertebrate body, and the patterning of the developing CNS is comprised of...
Financiado

NANOFATE: Nanoparticle Fate Assessment and Toxicity in the Environment National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: Concept: NanoFATE has been conceived to fill knowledge and methodological gaps currently impeding sound assessment of environmental risks po...
Financiado

FSES: Fast and slow endocytosis at the synapse National Centre for the Replacement Refinement and Reduction of Animals in Research NC3Rs tramitó un FP7: The mechanism of neurotransmitter release is a fundamental aspect of nervous system function, but it is still highly controversial. There is...
Financiado