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IMI2-2016-10-05
IMI2-2016-10-05: Biomanufacturing 2020: Development of Innovative high throughput analytical tools and methods to characterize cell culture fluid during development and commercial cell culture processes
Specific Challenge:Industrial Animal Cell Technology has become a well-established platform for biopharmaceutical production. However, substantial issues remain, calling for increased research and innovation. The absence of predictive tools and the poor understanding of how bioprocesses impact cell and protein quality increase production risks and costs. There is a need for the development of innovative analytical technology, leading to faster, leaner, more controllable, cost-effective and more industrious production. This should lead to more effective products manufactured by predictive, economic and competitive processes and thus to more cost savings that benefit both industry and healthcare systems, whilst ensuring safety.
Sólo fondo perdido 0 €
Europeo
Esta convocatoria está cerrada Esta línea ya está cerrada por lo que no puedes aplicar. Cerró el pasado día 28-03-2017.
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Presentación: Consorcio Consorcio: Esta ayuda está diseñada para aplicar a ella en formato consorcio.
Número mínimo de participantes.
Esta ayuda financia Proyectos: Objetivo del proyecto:

Specific Challenge:Industrial Animal Cell Technology has become a well-established platform for biopharmaceutical production. However, substantial issues remain, calling for increased research and innovation. The absence of predictive tools and the poor understanding of how bioprocesses impact cell and protein quality increase production risks and costs. There is a need for the development of innovative analytical technology, leading to faster, leaner, more controllable, cost-effective and more industrious production. This should lead to more effective products manufactured by predictive, economic and competitive processes and thus to more cost savings that benefit both industry and healthcare systems, whilst ensuring safety.


Scope:The overall objective is to develop/determine the best high throughput or novel analytical and/or feedback control methods/tests to be used for the parameters that need to be measured during manufacturing of biopharmaceuticals, in particular the cell culture.


Expected Impact: Innovative analytical tools developed by academic partners and SMEs can get translated, validated and implemented at larger companies for c... ver más

Specific Challenge:Industrial Animal Cell Technology has become a well-established platform for biopharmaceutical production. However, substantial issues remain, calling for increased research and innovation. The absence of predictive tools and the poor understanding of how bioprocesses impact cell and protein quality increase production risks and costs. There is a need for the development of innovative analytical technology, leading to faster, leaner, more controllable, cost-effective and more industrious production. This should lead to more effective products manufactured by predictive, economic and competitive processes and thus to more cost savings that benefit both industry and healthcare systems, whilst ensuring safety.


Scope:The overall objective is to develop/determine the best high throughput or novel analytical and/or feedback control methods/tests to be used for the parameters that need to be measured during manufacturing of biopharmaceuticals, in particular the cell culture.


Expected Impact: Innovative analytical tools developed by academic partners and SMEs can get translated, validated and implemented at larger companies for commercial purposes Creation of spin-offs specialized in these analytical tools. More effective control and execution of the production phase and will lead to the qualitative and consistent manufacturing of biopharmaceutical therapies Increase supply chain reliability and reduce drug shortages
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Temáticas Obligatorias del proyecto: Temática principal:

Características del consorcio

Ámbito Europeo : La ayuda es de ámbito europeo, puede aplicar a esta linea cualquier empresa que forme parte de la Comunidad Europea.
Tipo y tamaño de organizaciones: El diseño de consorcio necesario para la tramitación de esta ayuda necesita de:

Características del Proyecto

Requisitos de diseño: Duración:
Requisitos técnicos: Specific Challenge:Industrial Animal Cell Technology has become a well-established platform for biopharmaceutical production. However, substantial issues remain, calling for increased research and innovation. The absence of predictive tools and the poor understanding of how bioprocesses impact cell and protein quality increase production risks and costs. There is a need for the development of innovative analytical technology, leading to faster, leaner, more controllable, cost-effective and more industrious production. This should lead to more effective products manufactured by predictive, economic and competitive processes and thus to more cost savings that benefit both industry and healthcare systems, whilst ensuring safety. Specific Challenge:Industrial Animal Cell Technology has become a well-established platform for biopharmaceutical production. However, substantial issues remain, calling for increased research and innovation. The absence of predictive tools and the poor understanding of how bioprocesses impact cell and protein quality increase production risks and costs. There is a need for the development of innovative analytical technology, leading to faster, leaner, more controllable, cost-effective and more industrious production. This should lead to more effective products manufactured by predictive, economic and competitive processes and thus to more cost savings that benefit both industry and healthcare systems, whilst ensuring safety.
¿Quieres ejemplos? Puedes consultar aquí los últimos proyectos conocidos financiados por esta línea, sus tecnologías, sus presupuestos y sus compañías.
Capítulos financiables: Los capítulos de gastos financiables para esta línea son:
Personnel costs.
Los costes de personal subvencionables cubren las horas de trabajo efectivo de las personas directamente dedicadas a la ejecución de la acción. Los propietarios de pequeñas y medianas empresas que no perciban salario y otras personas físicas que no perciban salario podrán imputar los costes de personal sobre la base de una escala de costes unitarios
Purchase costs.
Los otros costes directos se dividen en los siguientes apartados: Viajes, amortizaciones, equipamiento y otros bienes y servicios. Se financia la amortización de equipos, permitiendo incluir la amortización de equipos adquiridos antes del proyecto si se registra durante su ejecución. En el apartado de otros bienes y servicios se incluyen los diferentes bienes y servicios comprados por los beneficiarios a proveedores externos para poder llevar a cabo sus tareas
Subcontracting costs.
La subcontratación en ayudas europeas no debe tratarse del core de actividades de I+D del proyecto. El contratista debe ser seleccionado por el beneficiario de acuerdo con el principio de mejor relación calidad-precio bajo las condiciones de transparencia e igualdad (en ningún caso consistirá en solicitar menos de 3 ofertas). En el caso de entidades públicas, para la subcontratación se deberán de seguir las leyes que rijan en el país al que pertenezca el contratante
Amortizaciones.
Activos.
Otros Gastos.
Madurez tecnológica: La tramitación de esta ayuda requiere de un nivel tecnológico mínimo en el proyecto de TRL 5:. Los elementos básicos de la innovación son integrados de manera que la configuración final es similar a su aplicación final, es decir que está listo para ser usado en la simulación de un entorno real. Se mejoran los modelos tanto técnicos como económicos del diseño inicial, se ha identificado adicionalmente aspectos de seguridad, limitaciones ambiéntales y/o regulatorios entre otros. + info.
TRL esperado:

Características de la financiación

Intensidad de la ayuda: Sólo fondo perdido + info
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Please read carefully all provisions below before the preparation of your application.
You can access the description of the different topics in the Call 10 topics text.
The budget breakdown for this Call is given at the end of the Call topics text, in the Conditions for this Call for proposals section, as well as the following information :
List of countries and applicable rules for funding
 
Eligibility and admissibility conditions
 
Evaluation criteria and procedure, scoring and treshold:  described in the IMI2 Manual for evaluation, submission and grant award.
 
Indicative timetable for evaluation and grant agreement
 
Provisions, proposal templates and evaluation forms for the type of actions under the Call topics:
IMI2 Research and Innovation Action (IMI2-RIA) and (IMI2-IA):
Summary of the most relevant provisions for participating in IMI2 actions
Proposal templates are available after entering the submission tool
Standard evaluation form
IMI2 Model Grant Agreement
Template for essential clinical trials information
 
Please read carefully all provisions below before the preparation of your application.
You can access the description of the different topics in the Call 10 topics text.
The budget breakdown for this Call is given at the end of the Call topics text, in the Conditions for this Call for proposals section, as well as the following information :
List of countries and applicable rules for funding
 
Eligibility and admissibility conditions
 
Evaluation criteria and procedure, scoring and treshold:  described in the IMI2 Manual for evaluation, submission and grant award.
 
Indicative timetable for evaluation and grant agreement
 
Provisions, proposal templates and evaluation forms for the type of actions under the Call topics:
IMI2 Research and Innovation Action (IMI2-RIA) and (IMI2-IA):
Summary of the most relevant provisions for participating in IMI2 actions
Proposal templates are available after entering the submission tool
Standard evaluation form
IMI2 Model Grant Agreement
Template for essential clinical trials information
 
Garantías:
No exige Garantías
No existen condiciones financieras para el beneficiario.

Información adicional de la convocatoria

Efecto incentivador: Esta ayuda tiene efecto incentivador, por lo que el proyecto no puede haberse iniciado antes de la presentación de la solicitud de ayuda. + info.
Respuesta Organismo: Se calcula que aproximadamente, la respuesta del organismo una vez tramitada la ayuda es de:
Meses de respuesta:
Muy Competitiva:
No Competitiva Competitiva Muy Competitiva
No conocemos el presupuesto total de la línea
Minimis: Esta línea de financiación NO considera una “ayuda de minimis”. Puedes consultar la normativa aquí.

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