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REWARDVIEW

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What you get is what you see How Reward Determines Perception

The expectation of a reward is known to be the driving force behind adaptive behaviour and learning. The effects of reward arise in dopaminergic reward circuitry at the centre of our primitive brain, which guides our goal-directed... ver más

30/04/2018

STICHTING VU

2M€

Presupuesto del proyecto: 2M€

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TRL 4-5

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Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2018-04-30 No tenemos la información de la convocatoria

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Líder del proyecto

STICHTING VU No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 2M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The expectation of a reward is known to be the driving force behind adaptive behaviour and learning. The effects of reward arise in dopaminergic reward circuitry at the centre of our primitive brain, which guides our goal-directed behaviour and fosters motivational control. A lot is known about the motivational effect of reward, but its effect on attention and perception has only marginally been explored. Recent studies from my lab suggest that such an effect of reward on perception is substantial and, crucially, arises instantly and is not related to a person’s motivation or strategy. Rewarding experiences change our brain: objects associated with reward appear to be more strongly represented in the visual cortex. This makes these objects to stand out from the environment. It makes that we perceive them, and focus on them, even when we try to ignore these objects. The research plan presented here will examine the neural response in early visual brain areas to objects associated with high versus low reward. We will measure the response of the brain, specifically the dopaminergic reward circuitry, when a reward is delivered. To investigate how these effects depend on dopamine, we plan to conduct studies involving Parkinson’s patients which allow us to directly manipulate the amount of dopamine in the brain. By means of deep brain stimulation, we link the effect even more tightly to the reward circuitry, by replacing reward by stimulation of this circuitry. As a final frontier we will relate individual reward sensitivity (a personality trait related to the mesolimbic dopamine system) to the development of addiction and risk seeking behaviour. The proposed research will have tremendous impact on the study of cognition, education, and (risky) decision making, as well as on a variety of clinical syndromes in which both attention and reward have been critically implicated, such as (drug) addiction and obesity.

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