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SENSiTRANS

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Visible-light-activated transmembrane transport by photosensitized isomerization...

Visible-light-activated transmembrane transport by photosensitized isomerization of stiff-stilbene based anion receptors Stimuli-responsive transmembrane anion transport proteins are essential for cellular life due to their implication in important biological functions. Supramolecular systems with analogous properties have been developed, however, m... ver más

31/08/2025

ULEI

Presupuesto desconocido

Líder del proyecto

UNIVERSITEIT LEIDEN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-09-01

HORIZON-MSCA-2022-PF-01-01: MSCA Postdoctoral Fellowships 2022 ExpectedOutcome:

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Duración del proyecto: 23 meses Fecha Inicio: 2023-09-01
Fecha Fin: 2025-08-31

Líder del proyecto

UNIVERSITEIT LEIDEN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Stimuli-responsive transmembrane anion transport proteins are essential for cellular life due to their implication in important biological functions. Supramolecular systems with analogous properties have been developed, however, most of them rely on the use of damaging UV light. SENSiTRANS is an ambitious and multidisciplinary project aimed at activation of anion transporters using visible light by means of a sensitization strategy. The project focuses on the employment of photosensitizers able to trigger isomerization of stiff-stilbene based receptors in the lipid bilayer, allowing activation of passive transmembrane transport. In addition, insertion of the photosensitizer in a vectorial manner into the lipid bilayer will be explored towards light-driven active transport. The project will result in i) the development of a new strategy to control transmembrane transport with transformative impact in the field of molecular photoswitches and anion receptor chemistry, ii) preparation and growth of the fellow towards a fully independent academic career (the new scientific research skills, complementary soft skills and scientific connections she will acquire will provide her with the necessary competencies to access an academic position at an European institution), and iii) benefit from her multidisciplinary scientific background and her scientific network by the hosting group.

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