Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

MOTOTRANS

Financiado

Cerrado

Light-driven molecular motors to trigger transmembrane transport of anions

"Anion transport through membranes, mediated by transport proteins, is one of the most important processes in living cells. Recently, a number of synthetic transmembrane anion transporters have been developed. However, unlike prot... ver más

30/06/2026

ULEI

Presupuesto desconocido

Líder del proyecto

UNIVERSITEIT LEIDEN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-07-01

HORIZON-MSCA-2023-PF-01-01: MSCA Postdoctoral Fellowships 2023 ExpectedOutcome:Project results are expected to contribute to the following outcomes:

I+D

Cerrada hace 1 año

0% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

Participantes

ULEI

Lider

Proyectos interesantes

LIGHTPORT From light stimulated anion receptors to transmembrane carri... 1M€ Cerrado

PID2020-117610RB-I00 SMALL MOLECULE TRANSMEMBRANE ANION CARRIERS FOR BIOLOGICAL A... 133K€ Cerrado

GRAIL Time-resolved imaging of membrane transporter dynamics under... 11M€ Cerrado

IJC2018-035283-I Physical mechanisms of ion and metabolite transport in viral... 93K€ Cerrado

VISUALTRANSPORT Visualizing Functional Structural Dynamics of Membrane Prote... 100K€ Cerrado

TRANSPORET Transmembrane Molecular Machines 1M€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Duración del proyecto: 23 meses Fecha Inicio: 2024-07-01
Fecha Fin: 2026-06-30

Líder del proyecto

UNIVERSITEIT LEIDEN No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto "Anion transport through membranes, mediated by transport proteins, is one of the most important processes in living cells. Recently, a number of synthetic transmembrane anion transporters have been developed. However, unlike proteins, they usually do not display responsive behaviour, making their function unspecific. There are only a few methods known for controlling the transport function of these receptors by physiochemical stimuli, with using light being one of the most well-known. These stimuli-responsive receptors, however, only alternate between distinct ""on"" and ""off"" states, while biomolecular systems are able to use the motion of motor proteins to regulate the passage of ions. Two first studies have shown that rotating molecular motors can enhance cation transport through membrane-spanning channels, possibly by influencing conformational dynamics. However, there have been no detailed studies that take advantage of subtle changes in membrane characteristics. It would be very promising to enhance and regulate anion transport across the membrane by integrating molecular machine-like entities into lipid bilayers and synthetic transport systems. MOTOTRANS is a multidisciplinary project that aims to develop transmembrane anion transport systems containing light-driven molecular motors. The out-of-equilibrium rotational dynamics of light-driven molecular motors could influence either membrane, carrier or channel properties, resulting in enhanced transport activity, which will be investigated in work packages 1-3, respectively. The project will have three major impacts: an innovative approach with profound implications in molecular machines and transmembrane anion transport; a significant impact on the fellow's academic career, acquiring new research skills, complementary skills, and scientific connections, enabling access to an academic position in Europe; and the host group and institution will benefit from the fellow's diverse scientific background and network."

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores