Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

AmygdalaNeuroMod

Financiado

Cerrado

Unraveling the combinatorial logic of amygdala neuromodulation in decision makin...

Unraveling the combinatorial logic of amygdala neuromodulation in decision making and learning. Proper neuronal circuit function depends fundamentally on the balance of neuromodulators, a set of neurotransmitters released widely throughout the brain. Almost every mental disorder, including anxiety and depression, that affect... ver más

31/05/2023

FMI

191K€

Presupuesto del proyecto: 191K€

Líder del proyecto

FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL R... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-05-31

MSCA-IF-2018: Individual Fellowships

I+D

Cerrada hace 6 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

FMI

191.15K€ | Lider

Proyectos interesantes

INTENDeD

Medical Technol...

Applied Physics

203K€ Cerrado

SAF2009-06983

Medical Technol...

Applied Physics

109K€ Cerrado

PID2019-108725RB-I00

Medical Technol...

Applied Physics

132K€ Cerrado

OPTONEUROMOD

Medical Technol...

Applied Physics

1M€ Cerrado

PID2020-112705RB-I00

Medical Technol...

Applied Physics

284K€ Cerrado

AMY-MPFC-EXTINCTION

Medical Technol...

Applied Physics

100K€ Cerrado

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Duración del proyecto: 50 meses Fecha Inicio: 2019-03-19
Fecha Fin: 2023-05-31

Líder del proyecto

FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL R... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 191K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Proper neuronal circuit function depends fundamentally on the balance of neuromodulators, a set of neurotransmitters released widely throughout the brain. Almost every mental disorder, including anxiety and depression, that affect one out of four Europeans, are associated with a neuromodulatory imbalance in specific sub-circuits. Elucidating the role of different neuromodulatory inputs to specific brain regions holds the keys to understanding and treating mood disorders. The amygdala plays an essential role in the processing of emotional stimuli and salience, ranging from reward to threat and synaptic alterations in this region are critical for learning and emotional processing. Amygdala is innervated by every major neuromodulator, yet surprisingly little is known about the activity of these inputs under physiological conditions and how neuromodulation regulates amygdala circuit activity during different behavioral states and learning. Here, I propose to study the functional role of neuromodulatory inputs to the amygdala circuitry during learning and decision-making. Towards this goal, I will combine my experience in large-scale electrophysiology with the expertise of the host laboratory in modern genetic tools and neurotechnologies to simultaneously record and manipulate the activity of dopamine, serotonin, norepinephrine and acetylcholine inputs to the amygdala during context-guided decision-making in behaving mice. Using this approach, I aim to characterize the logic of interactions between neuromodulators and its implementation at the level of defined circuits and cell types in the amygdala and to demonstrate the role of this coordination in defining network activity, behavioral state and learning. The fellowship will contribute to our basic understanding of the interplay between two core brain systems, while it will provide me with a unique opportunity to expand my expertise and establish the foundations of my future career as an independent group leader.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores