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NTS-EXPOSURE

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The innovative wastewater based epidemiology approach with the advances of high...

The innovative wastewater based epidemiology approach with the advances of high resolution mass spectrometry as a complementary biomonitoring tool for assessing the health status of a population Humans are continuously exposed to toxicants by different routes, with potentially adverse effects on human health. Monitoring population exposure is a crucial part of public health programs and human biomonitoring (HBM) is the mo... ver más

31/10/2023

UOA

248K€

Presupuesto del proyecto: 248K€

Líder del proyecto

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINO... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-10-31

MSCA-IF-2019: Individual Fellowships Objective:The goal of the Individual Fellowships is to enhance the creative and innovative potential...

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2 Participantes

UOA

248.02K€ | Lider

THE UNIVERSITY OF QUEENSLAND

N.D. | Participante

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Duración del proyecto: 42 meses Fecha Inicio: 2020-04-03
Fecha Fin: 2023-10-31

Líder del proyecto

ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINO... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 248K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Humans are continuously exposed to toxicants by different routes, with potentially adverse effects on human health. Monitoring population exposure is a crucial part of public health programs and human biomonitoring (HBM) is the most widely used and powerful tool to evaluate the exposure of a population. These data are vital for health impact assessment and to support environmental and health policy-making in public health programs. However, novel approaches are needed in order to give additional information on exposure at population level and overcome the limitations of HBM studies. In this project, an innovative approach, called Wastewater-Based Epidemiology (WBE), is proposed as an alternative biomonitoring tool for the retrieval of epidemiological information from wastewater through the analysis of specific human urinary metabolites (biomarkers). Although WBE has been studied the last fifteen years, its application has been limited to target analytical methods and a few classes of compounds (i.e. illicit drugs). New methodologies such as the powerful high resolution mass spectrometry (HRMS) technique can opens new perspectives in the WBE field. The unique characteristics of HRMS combined with the potential of the WBE approach can give us the capability to provide valuable information for public health. Indeed, influent wastewater contains a wide range of chemical information about biological processes of the human body, which can be explored by the latest advances of HRMS and provide crucial data. The main objective is to develop non-target screening analytical methods based on HRMS coupled to liquid and gas chromatography that can detect new wastewater biomarkers and assess the collective consumption or exposure to toxicants. This project can establish and implement an integrated chemical analytical-epidemiological approach for the acquirement of crucial information and inform authorities and public health organizations on community health status.

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