IMAGEN3D
Financiado
The hidden majority: high-resolution imaging and genomics of the most ecological...
The hidden majority: high-resolution imaging and genomics of the most ecologically important microbial eukaryotes in the ocean
How have eukaryotes evolved into the vast diversity we see nowadays? At present this simple question remains a mystery, mostly due to the vast uncharted microbial environmental diversity recurrently unveiled by molecular surveys....
How have eukaryotes evolved into the vast diversity we see nowadays? At present this simple question remains a mystery, mostly due to the vast uncharted microbial environmental diversity recurrently unveiled by molecular surveys. This gap in knowledge hinders a deep understanding of basic eukaryotic diversity, evolution and biology, and creates a biased perception towards well-characterized organisms of human interest. Yet, since the beginning of microbial research, from Leeuwenhoek and Haeckel, unicellular eukaryotes have been largely studied by optical methods, describing an extensive variety of shapes and morphologies. We therefore need new and different approaches to explore unknown eukaryote diversity.
The goal of this project is to better understand early and enigmatic eukaryotic evolution by studying the morphology and genomes of the most informative undescribed eukaryotic lineages. Studies of novel eukaryotic diversity have historically relied on arbitrary factors regardless of their environmental abundance due to the lack of data. Yet, abundant groups are the most practical to explore. I will first identify the most environmentally abundant species that are distantly related to morphologically described groups. Next, I will develop a novel approach that allows the acquisition of 3D morphological data by imaging group-specific fluorescence in situ hybridization probes in combination with a set of fluorescent dyes labeling relevant subcellular features. Finally, I will sequence and assemble their genomes to better resolve the eukaryotic tree of life, by filling out poorly represented lineages that are distantly related to well-characterized species. This project will bring for the first time the link between already available environmental short sequences and their organismal morphology and genomic data.
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Duración del proyecto: 40 meses
Fecha Inicio: 2023-04-06
Fecha Fin: 2026-08-31
Fecha Fin: 2026-08-31
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-04-06
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2022-PF-01-01:
MSCA Postdoctoral Fellowships 2022
Cerrada
hace 2 años
Presupuesto
El presupuesto total del proyecto asciende a
181K€
Líder del proyecto
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGA...
Investigaciones agrarias
Perfil tecnológico
TRL
2-3
552M
Perfil tecnológico
TRL
2-3
552M