The effect of a sedentary lifestyle on type 2 diabetes and its complications
Low physical activity is a well-known risk factor of many healthy problems. It is, however, not clear whether the increased health risks are due to lack of moderate to vigorous activity or due to a more sedentary lifestyle. Sedent...
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Información proyecto SEDIAB
Líder del proyecto
UNIVERSITEIT MAASTRICHT
No se ha especificado una descripción o un objeto social para esta compañía.
TRL
4-5
Presupuesto del proyecto
100K€
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
Low physical activity is a well-known risk factor of many healthy problems. It is, however, not clear whether the increased health risks are due to lack of moderate to vigorous activity or due to a more sedentary lifestyle. Sedentary behaviour cannot simply be defined as the lack of moderate to vigorous activity but is defined as engaging in activities which marginally increase energy expenditure above resting level such as sitting, using the computer, and watching television. Understanding the health consequences of sedentary behaviour independently and jointly associated with physical activity is essential in order to promote healthy behaviours and more effective guidelines.
In the present proposal we aim to disentangle the relation between objectively measured sedentary behaviour and physical activity in relation to type 2 diabetes and diabetic complications in the Maastricht Study in the Netherlands. The Maastricht Study is a large newly established cohort study focusing on the determinants and consequences of type 2 diabetes. Using the innovative activPAL™ accelerometer we will be able to examine daily activity across the full range of activity intensities. The objectives of the current proposal are:
1) to describe and compare patterns of daily activity among people with diabetes, prediabetes and those without type 2 diabetes;
2) to examine the association between sedentary behaviour and prevalent and incident (pre)diabetes and to understand whether this is independent of physical activity; and
3) to examine the relation between sedentary behaviour and prevalent and incident diabetic complications and to understand whether this is independent of physical activity.
This research will both advance the physical activity research field and the diabetes field. The discoveries of the project are expected to have important public health impact and can affect both physical activity guidelines and guidelines to prevent/delay type 2 diabetes and its complications.