Innovating Works

SUSAMIDE

Financiado
Sustainable Synthesis of Amides
Despite the ubiquity of the amide group, its synthesis is not always straightforward and the existing methods for amide formation score badly from the perspectives of economy and sustainability. This proposal aims to develop unpr... Despite the ubiquity of the amide group, its synthesis is not always straightforward and the existing methods for amide formation score badly from the perspectives of economy and sustainability. This proposal aims to develop unprecedented methodology for amide synthesis, allowing one to access challenging representatives. Two routes are proposed to mitigate risk and to provide complementarity. The objective of the proposal is twofold: 1) to expand the available chemical space (allowing one to synthesize challenging amides previously considered inaccessible via library synthesis with existing methods) and 2) to substitute existing syntheses with better ones (delivering higher yields without using toxic reagents and minimizing waste). Achieving these two objectives will have an impact on the discovery of new molecular entities and the improvement of production processes in the fine chemicals sector. The power of the new methodology will be demonstrated on the synthesis of selected real-life examples, APIs (Active Pharmaceutical Ingredients). ver más
31/03/2017
173K€
Duración del proyecto: 24 meses Fecha Inicio: 2015-03-17
Fecha Fin: 2017-03-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2017-03-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
Presupuesto El presupuesto total del proyecto asciende a 173K€
Líder del proyecto
UNIVERSITEIT ANTWERPEN No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5