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BoldJet

Financiado

Skin micro-injector

Needle-based injections are very common in modern medicine, notably in ongoing vaccination efforts worldwide. However, needle phobia and infection risks affect patient compliance with medical treatments, while millions of used nee... ver más

30/11/2023

UNIVERSITEIT TWENT...

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

UNIVERSITEIT TWENTE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-11-30

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

ERC-2022-POC1: ERC PROOF OF CONCEPT GRANTS1

I+D

Cerrada hace 3 años

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1 Participantes

UNIVERSITEIT TWENTE

150.00K€ | Lider

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Últimas noticias

29-11-2024: IDAE En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones

29-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones

29-11-2024: CMVAMADRID En las últimas 48 horas el Organismo CMVAMADRID ha otorgado 37 concesiones

Duración del proyecto: 18 meses Fecha Inicio: 2022-05-12
Fecha Fin: 2023-11-30

Líder del proyecto

UNIVERSITEIT TWENTE

TRL 4-5

Presupuesto del proyecto 150K€

Descripción del proyecto Needle-based injections are very common in modern medicine, notably in ongoing vaccination efforts worldwide. However, needle phobia and infection risks affect patient compliance with medical treatments, while millions of used needles contaminate the environment. Lastly, the effectiveness of certain drugs increases when injected intradermally, but targeting the dermis is challenging. Thus, new minimal-invasive procedures are needed. Jet injectors are needle-free medical devices that pressurize thin liquid filaments to penetrate the skin. Jet injections have been effective in subcutaneous and intramuscular delivery, ex vivo, and in vivo. However, the expected needle-free revolution for medical treatments has neither been fulfilled, nor widely commercialized due to factors such as: a) Bruising, a painful consequence of delivering large volumes in a single location. b) When using wrong energy settings, or misalignment with respect to the skin, the injected liquid can perfuse other layers. c) The rejected liquid splashes back, leading to an incorrect dose delivery, risks of cross contamination of the injector parts, or splash-back on the care giver. d) Commercial jet injection methods, such as springs or compressed gas, are noisy which can distress the patient. Hence, there is a need to develop a new way to deliver smaller doses with maximum accuracy in targeting specific skin layers. Bold-Jet is aimed at revolutionizing the experience of people who receive or perform frequent injections by developing for the first time a needle-free device using microjets that is safer, minimally invasive, and eco-friendly. By avoiding the use of needles, we can increase adherence to treatments by patients with fear to sharps and expand clinical routes for existing drugs and treatment.

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