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BTech

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Cerrado

Novel human neurodegenerative disease specific 3D cell models with applications...

Novel human neurodegenerative disease specific 3D cell models with applications in drug development and toxicity testing Drug development for Parkinson’s disease, Alzheimer’s disease, and further neurodegenerative diseases is struggling due to high failure rate and high costs. BTech is a new 3D in vitro Brain-on-a-Chip technology that can offer medi... ver más

31/05/2018

BTech SARL

71K€

Presupuesto del proyecto: 71K€

Líder del proyecto

BRAINGINEERING TECHNOLOGIES SARL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2018-05-31

SMEInst-03-2016-2017: Dedicated support to biotechnology...

I+D

Cerrada hace 8 años

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

BTech SARL

50.00K€ | Lider

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Duración del proyecto: 4 meses Fecha Inicio: 2018-01-31
Fecha Fin: 2018-05-31

Líder del proyecto

BRAINGINEERING TECHNOLOGIES SARL No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 71K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Drug development for Parkinson’s disease, Alzheimer’s disease, and further neurodegenerative diseases is struggling due to high failure rate and high costs. BTech is a new 3D in vitro Brain-on-a-Chip technology that can offer medium-throughput screening of drugs during pre-clinical testing that more accurately reflects the effects of drugs on humans than conventional 2D cell cultures and mouse models. The technology is based on microfluidics where cells are cultured in three dimensional hydrogel environments mimicking the conditions in vivo. BTech provides solutions for pharmaceutical companies, specialised biotech companies and academic researchers to test novel drug compounds with applications in neurodegenerative disorders and for toxicity testing. The business model is based on two applications: • As a Service in it`s own the laboratory, BT cultivates human stem cell derived neurons and midbrain organoids and then evaluates the application of customers’ compounds on them. • As a Product, the company offers ready-made midbrain organoids. These organoids are 3D structures with specialized brain cells that are spatially and functionally organized to mimic the physiological state of the human brain. The organoids are sold and shipped to customers and used directly by them as a research material or a pre-clinical model. During Phase 1, the feasibility assessment will focus on following technical and business objectives during its 6 months, to develop a robust plan for Phase 2, which intend to reach the industrial stage of development and commercialize BTech on the market. It intend to scout and involve companies from the pharma industry, such as Sanofi, Evotec AG, Farcoderm or UCD to validate in Phase 2 the software, platform and processes, by performing 2 test with a total of 20 compounds.

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