Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

DECISIONSEQ

Financiado

Cerrado

Neural bases of behavioral choices and sequences

It is essential for survival across the animal kingdom to make appropriate choices depending on the environmental context and the internal state. Nevertheless, how decision-making is implemented in the nervous system by specific c... ver más

07/12/2020

173K€

Presupuesto del proyecto: 173K€

Líder del proyecto

INSTITUT PASTEUR No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2020-12-07

MSCA-IF-2017: Individual Fellowships

I+D

Cerrada hace 7 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

173.08K€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

NEODYNE Decision making from neurochemical mechanisms to network dy... 2M€ Cerrado

PRIORS Neural circuit dynamics underlying expectation and their imp... 2M€ Cerrado

CODIR Cortical Dynamics of Decision Irrationality 171K€ Cerrado

ACTSELECTCONTEXT Action Selection under Contextual Uncertainty the Role of L... 1M€ Cerrado

FLEXNEURO Flexible and robust nervous system function from reconfiguri... 1M€ Cerrado

RISKYREWARDS Neuronal processing of risky rewards 2M€ Cerrado

Duración del proyecto: 31 meses Fecha Inicio: 2018-05-02
Fecha Fin: 2020-12-07

Líder del proyecto

INSTITUT PASTEUR No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 173K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto It is essential for survival across the animal kingdom to make appropriate choices depending on the environmental context and the internal state. Nevertheless, how decision-making is implemented in the nervous system by specific circuits remains a significant gap in our knowledge. Many actions are physically mutually exclusive so competitive interactions must exist to enable the selection of one behavior and concomitant full suppression of all alternatives. Often, behaviors are not single actions but multiple actions organized into sequences that allow the animals to achieve their goals and mechanisms must be in place to regulate the transition between the behaviors in a sequence. Here again the network architecture underlying the generation of action sequences is not known with synaptic resolution. The difficulty in determining the detailed network architectures underlying decision-making and sequence generation is primarily due to the challenges in mapping connectivity between neurons with synaptic resolution and establishing causality between neurons and behaviors with cellular resolution with the model systems used. We propose to study circuit mechanisms of selection, repression and transitions between actions and fill the above described knowledge gap. Our multidisciplinary approach will combine neural manipulation during behavior, electron microscopy (EM) reconstruction of neuronal connectivity with synaptic resolution in the tractable model system, the Drosophila larva with modeling and quantitative behavioral analysis. We aim at determining with unprecedented resolution the network architectures and circuit mechanisms underlying competitive interactions and sequence transitions. Determining basic principles of behavioral choice and sequence implementation in the tractable genetic model system will lay the basis for future investigations in larger, more complex systems.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores