Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

MMEMA

Financiado

Cerrado

Molecular mechanisms for the evolution of multicellularity in animals

The evolution of multicellular animals (metazoans) from a unicellular ancestor is one of the most significant leaps in the history of life. However, little is known about the mechanisms that enabled it. Upon the acquisition of mul... ver más

31/03/2011

218K€

Presupuesto del proyecto: 218K€

Líder del proyecto

UNIVERSIDAD DE BARCELONA No se ha especificado una descripción o un objeto social para esta compañía.

Total investigadores 328

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo FP7 notifico la concesión del proyecto el día 2011-03-31 No tenemos la información de la convocatoria

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

0.00€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

FlexAggon Evolutionary origin of cell adhesion: the basis of multicell... 196K€ Cerrado

BFU2008-00227 INVESTIGACIONES CITOLOGICAS Y MOLECULARES EN ESTADOS EVOLUTI... 103K€ Cerrado

PRO2EUK Exploring Asgard archaea to illuminate the prokaryote to euk... 2M€ Cerrado

PID2020-120609GB-I00 EL ORIGEN DE LOS ANIMALES; UNA APROXIMACION FUNCIONAL Y DE B... 351K€ Cerrado

MULTICELLEXPEVO Reconstructing the origins of animal multicellularity using... 158K€ Cerrado

PREMETAZOANEVOLUTION Unravelling the unicellular prehistory of metazoans with fun... 2M€ Cerrado

Líder del proyecto

UNIVERSIDAD DE BARCELONA No se ha especificado una descripción o un objeto social para esta compañía.

Total investigadores 328

Presupuesto del proyecto 218K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The evolution of multicellular animals (metazoans) from a unicellular ancestor is one of the most significant leaps in the history of life. However, little is known about the mechanisms that enabled it. Upon the acquisition of multicellularity, many molecular level innovations should have occurred, especially in the systems responsible for cell adhesion, differentiation, and cell-cell communication. Investigation of a group of protists (unicellular or colonial eukaryotes) that is closely related to metazoans should provide deep insights into molecular mechanisms for this event. Among such protists, however, only unicellular choanoflagellates have been extensively studied so far. This project aims to fill this missing piece by applying comparative genomics and molecular biological approaches to Codonosiga botrytis, a colonial choanoflagellate and two additional protists Sphaeroforma arctica and Capsaspora owczarzaki, which were recently shown to be closely related to metazoans, like choanoflagellates. To this aim, 1) the complete genome sequences of Sphaeroforma and Capsaspora, which will be exclusively available in the host institute, will be analyzed and compared to those of metazoans, in order to identify the candidate genes that were relevant to the evolution of multicellularity. Then 2) the difference in the expression profiles between the colonial and unicellular stages of Sphaeroforma and Codonosiga will be studied to identify genes responsible for forming the colony, which might represent the ‘ancestral form’ of multicellularity in metazoans. Finally, 3) molecular biological methods will be developed and applied to these protists, and functions of the candidate genes identified in 1) and 2) will be analyzed. This should elucidate the functional ‘innovations’ that enabled the evolution of multicellularity. These data will have a major impact to a wide range of research fields, especially to the ‘evo-devo’, microbiology, and molecular evolution communities.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores