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Modelling to Optimize Vector Elimination Destabilising mosquito populations

Control of vector-borne diseases from Chagas to Malaria to Dengue largely relies on reducing or eliminating the arthropod vector populations. These public health initiatives routinely lead to at least initial declines in vector po... ver más

30/04/2026

UNIVERSITY OF GLAS...

1M€

Presupuesto del proyecto: 1M€

Líder del proyecto

UNIVERSITY OF GLASGOW No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 2 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2019-10-30

ERC-2019-STG: ERC Starting Grant

I+D

Cerrada hace 6 años

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

2 Participantes

UNIVERSITY OF GLASGOW

1.26M€ | Lider

ALBATROS, SL

629.46K€ | Participante

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Duración del proyecto: 78 meses Fecha Inicio: 2019-10-30
Fecha Fin: 2026-04-30

Líder del proyecto

UNIVERSITY OF GLASGOW No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 1M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Control of vector-borne diseases from Chagas to Malaria to Dengue largely relies on reducing or eliminating the arthropod vector populations. These public health initiatives routinely lead to at least initial declines in vector populations. The challenge is that as populations decline, unexpected evolutionary (such as insecticide resistance) and ecological changes (such as population fragmentation and altered density-dependence) can occur that might facilitate or undermine control efforts. However, the relative importance of these ecological intra- and inter-specific processes in regulating vector populations is almost unknown, which hinders the prediction of vector population dynamics and how different interventions might be most effectively deployed to sustainably suppress vectors. Although vector surveillance has generated extensive high-resolution time series datasets to assess the factors that underpin population persistence and regulation, the cutting-edge analytical tools required to overcome the complexity of these data have been mostly developed by ecologists and have rarely been applied in medical entomology. Filling both these knowledge and methodological gaps will require closer integration of public health science, medical entomology and ecology that I intend to deliver through this proposal. As a quantitative ecologist, I will work closely with medical entomologists and public health scientists, to develop and apply sophisticated state-space models to longitudinal vector surveillance data from five malaria endemic countries. I will determine how interventions impact vector: 1) population regulation, 2) metapopulation connectivity and persistence, and 3) community composition. This unprecedented demographic dissection of vector populations will simultaneously challenge ecological theory and explore how to harness intra- and inter-specific processes in vector populations to accelerate 'end-game' strategies that move from vector control to elimination.

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