CRMS
Financiado
Microfluidic Diffusion-based Chiral Resolution
Chirality is an essential property of nature, producing and regulating fundamental phenomena in living matter. Chiral compounds are widely used in medicine, clinical, pathological, and other fields. Different enantiomers of chiral...
Chirality is an essential property of nature, producing and regulating fundamental phenomena in living matter. Chiral compounds are widely used in medicine, clinical, pathological, and other fields. Different enantiomers of chiral molecules have significant differences in pharmacological activities, metabolic effects, toxicity, and even opposite effects. Since most chiral compounds exist in the racemic form, it is important to develop strategies for rapid and efficient separation and purification of chiral compounds to deal with inevitable future threats such as diseases and viruses. Although many techniques for chiral resolutions have been developed over the years, most of them are impeded by low efficiency and accuracy, high energy consumption, tedious preparation and operation and high cost. Therefore, I propose a project, CRMS Chiral Resolution using Microfluidics and helical Supramolecular polymers which aims to develop a simple diffusion-based strategy for chiral resolution by incorporating helical supramolecular polymers (HSPs). In this project, I will combine the ability of HSPs to recognize the handedness of chiral molecules through non-covalent interactions with the diffusion-based separation ability of microfluidics for the enantio-separation of chiral molecules. I chose microfluidics for chiral resolution because it is a cost-effective and energy-efficient technique that takes advantage of the natural flow properties of the fluids entering the flow reactor for diffusion-based separation. CRMS project will not only start a new area of research in the junction of supramolecular chirality and flow chemistry but also have applications in pharmaceutical and cosmetic industries for enantio-separation of chiral drugs/ingredients.
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Duración del proyecto: 24 meses
Fecha Inicio: 2023-04-05
Fecha Fin: 2025-04-30
Fecha Fin: 2025-04-30
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-04-05
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2022-PF-01-01:
MSCA Postdoctoral Fellowships 2022
Cerrada
hace 2 años
Presupuesto
El presupuesto total del proyecto asciende a
190K€
Líder del proyecto
FUNDACION IMDEA NANOCIENCIA
Otra investigación y desarrollo experimental en ciencias naturales y técnicas asociacion
Perfil tecnológico
TRL
4-5
130K
Perfil tecnológico
TRL
4-5
130K
61.76K€ |
Participante