LCT
Financiado
Localized Cancer Therapy
Currently, cancer is the second cause of morbidity and death in Europe, with 1.9m deaths and 3.7m cases annually. Cancer-related deaths are projected to exceed 13m by 2030, with abdominal organs hosting most cancer incidents. Alth...
Currently, cancer is the second cause of morbidity and death in Europe, with 1.9m deaths and 3.7m cases annually. Cancer-related deaths are projected to exceed 13m by 2030, with abdominal organs hosting most cancer incidents. Although popular, conventional modalities are nonetheless associated with major clinical challenges such as non-specificity, side effects, and drug tolerance, which impede further developments. In recent years, non-invasive, controllable, minimal side effects, and localized nano-scale drug-based therapies have been developed. This treatment deploys nanocarriers (NCs) to the location of the targeted cancer tumors, and upon activation, they release chemotherapeutic drugs. However, there are concerns over the safety of this strategy due to lack of biodegradation, potential toxicity, poor bioavailability, and limitations associated with the drug activation protocols. The main goal of the LCT project is to overcome these challenges in an original and innovative manner by developing nanocarriers that are nontoxic, biocompatible, biodegradable, and can be combined with a well-known treatment modality (e.g., a precise and effective radiation treatment). The proposed work will be approached from theoretical, numerical, and experimental perspectives based on the applicant's and host laboratory's expertise. The training program is exhaustive and will allow the applicant to grow as an independent researcher. The proposed research will foster further development in this direction, a step that is fundamental in healthcare and for the benefit of society.The applicant is a Libyan scholar with expertise in the areas of applied mechanics, industrial & medical radiation, materials science, nano-chemistry, and structural engineering. He has been trained in prestigious industrial and academic institutions in Libya, Canada, and Hong Kong. He is applying for a two-year MSCA fellowship to conduct the LCT at NUI Galway. A 4 months secondment at UCD is planned.
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Duración del proyecto: 23 meses
Fecha Inicio: 2023-01-02
Fecha Fin: 2025-01-01
Fecha Fin: 2025-01-01
Línea de financiación: concedida
El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-01-02
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
HORIZON-MSCA-2021-PF-01-01:
MSCA Postdoctoral Fellowships 2021
Cerrada
hace 3 años
Líder del proyecto
UNIVERSITY OF GALWAY
No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5