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PerMedCoE

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HPC Exascale Centre of Excellence in Personalised Medicine PerMedCoE

Personalised Medicine (PerMed) opens unexplored frontiers to treat diseases at the individual level combining clinical and omics information. However, the performances of the current simulation software are still insufficient to t... ver más

31/12/2023

BARCELONA SUPERCOM...

5M€

Presupuesto del proyecto: 5M€

Líder del proyecto

BARCELONA SUPERCOMPUTING CENTERCENTRO NACIONA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5 | 118M€

Fecha límite participación Sin fecha límite de participación.

Ver 14 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2023-12-31

INFRAEDI-05-2020: Centres of Excellence in exascale c...

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14 Participantes

BARCELONA SUPERCOMPUTING CEN...

1.19M€ | Lider

FUNDACIO INSTITUT DE RECERCA...

42.50K€ | Participante

INSTITUT CURIE FONDATION

508.75K€ | Participante

UKHD

473.50K€ | Participante

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Duración del proyecto: 40 meses Fecha Inicio: 2020-08-11
Fecha Fin: 2023-12-31

Líder del proyecto

BARCELONA SUPERCOMPUTING CENTERCENTRO NACIONA... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5 | 118M€

Presupuesto del proyecto 5M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Personalised Medicine (PerMed) opens unexplored frontiers to treat diseases at the individual level combining clinical and omics information. However, the performances of the current simulation software are still insufficient to tackle medical problems such as tumour evolution or patient-specific treatments. The challenge is to develop a sustainable roadmap to scale-up the essential software for the cell-level simulation to the new European HPC/Exascale systems. Simulation of cellular mechanistic models are essential for the translation of omic data to medical relevant actions and these should be accessible to the end-users in the appropriate environment of the PerMed-specific big confidential data. The goal of the HPC/Exascale Centre of Excellence in Personalised Medicine (PerMedCoE) is to provide an efficient and sustainable entry point to the HPC/Exascale-upgraded methodology to translate omics analyses into actionable models of cellular functions of medical relevance. It will accomplish so by 1) optimising four core applications for cell-level simulations to the new pre-exascale platforms; 2) integrating PerMed into the new European HPC/Exascale ecosystem, by offering access to HPC/Exascale-adapted and optimised software; 3) running a comprehensive set of PerMed use cases; & 4) building the basis for the sustainability of the PerMedCoE by coordinating PerMed and HPC communities, and reaching out to industrial and academic end-users, with use cases, training, expertise, and best practices. The PerMedCoE cell-level simulations will fill the gap between the molecular- and organ-level simulations from the CompBioMed and BioExcel CoEs with which this proposal is aligned at different levels. It will connect methods’ developers with HPC, HTC and HPDA experts (at POP and HiDALGO CoEs). Finally, the PerMedCoE will work with biomedical consortia (i.e. ELIXIR, LifeTime initiative) and pre-exascale infrastructures (BSC and CSC), including a substantial co-design effort.

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