Descripción del proyecto
The Extracellular vesicles (EV) field is growing due to increased interest in their roles in diagnostics and therapeutics. Current methods to purify and quantify EV’s take a long time, introduce a bias, are costly and imprecise, thereby hampering advancement in the EV R&D field, while the lack of methods to quantify EVs directly in crude samples restricts applications in diagnostic and bioprocessing. FOX has established a breakthrough label-free technology in a fiber-optic concept in an automated platform that allows biomolecular interaction research of biologicals. The FOx affinity isolation and simultaneous quantification with a sensor dip probe is a new, selective (no bias), automated (scalable 4x), faster (time/24) and specific (purity >95%) method that allows accurately quantifying EV directly from crude samples. Moreover, it allows for the first time to release the quantified and specifically selected EV’s for further quantitative content analysis.