Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

RNA-top

Financiado

RNA topology of test samples and single extracellular vesicles: how cells packag...

RNA topology of test samples and single extracellular vesicles: how cells package RNA messages to communicate (RNA-top) In RNA-top, I will investigate the precise location(s) and quantity of RNA associated with extracellular vesicles (e.g. EV-RNA topology). To achieve this goal, I will set-up innovative liposome-based synthetic vesicle models (hera... ver más

31/07/2025

STICHTING AMSTERDA...

235K€

Presupuesto del proyecto: 235K€

Líder del proyecto

STICHTING AMSTERDAM UMC No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 3 Participantes

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-06-27

HORIZON-MSCA-2021-PF-01-01: MSCA Postdoctoral Fellowships 2021 ExpectedOutcome:

I+D

Cerrada hace 3 años

0% 100% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

3 Participantes

STICHTING AMSTERDAM UMC

234.53K€ | Lider

Exometry BV

N.D. | Participante

HUN-REN RESEARCH CENTRE FOR...

N.D. | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

EV FOx Extracellular Vesicles Fiber Optic Surface Plasmon Resonance... 4M€ Cerrado

Exosomes Regulated secretion and role of urinary nanovesicles 200K€ Cerrado

CROSSTALK Decoding Extracellular Vesicle-mediated organ crosstalk in v... 2M€ Cerrado

UNRAVEL Unravelling extracellular vesicle heterogeneity to inspire i... 2M€ Cerrado

NEXUS automated in-line separatioN and dEtection of eXtracellular... 2M€ Cerrado

AcouSome Acoustofluidic thin-film actuated chip for exosome separatio... 2M€ Cerrado

Duración del proyecto: 37 meses Fecha Inicio: 2022-06-27
Fecha Fin: 2025-07-31

Líder del proyecto

STICHTING AMSTERDAM UMC No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 235K€

Descripción del proyecto In RNA-top, I will investigate the precise location(s) and quantity of RNA associated with extracellular vesicles (e.g. EV-RNA topology). To achieve this goal, I will set-up innovative liposome-based synthetic vesicle models (herafter referred to as test samples), resembling EVs, with a known RNA topology. I will use these test samples to create workflows for super resolution microscopy (SRM) and spectral flow cytometry (sFCM) to study RNA topology. These workflows will be extrapolated to EV samples, to define EV-RNA topology of single EVs for the first time. The research will be conducted in the Amsterdam UMC under the supervision of Dr. Rienk Nieuwland. Nieuwland and his team have the knowledge, experience and technical infrastructure to perform SRM and sFCM to study EVs. Therefore, RNA-top will allow me to deepen my knowledge on EVs and gain skills to perform SRM and sFCM. Conversely, I will bring my expertise in liquid biopsies and RNA, obtained during my PhD in Pangaea Oncology in Barcelona (H2020-MSCA-ITN). I will carry out a secondment in the lab of Dr. Zoltán Varga (Research Center for Natural Sciences in Budapest), an expert in the field of creating test samples, to get hands-on training. At the end of the project, I will join Exometry, supervised by Dr. Edwin van der Pol (CSO), for a 6-month non-academic placement to (1) develop an analysis software to process RNA topology data and (2) gain commercialization skills. The unique interdisciplinary and inter-sectoral combination of the participating organizations and myself, unites all the expertise and infrastructure required to reach the objectives of RNA-top.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores