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BIOMIMIC

Financiado

Cerrado

BIOphysics of MIcrobe Microplastic Interactions and Colonization

Aquatic microbes - both marine and freshwater - drive global biogeochemical cycles. However, owing to the influx of microplastics (MPs) in their natural ecosystems, microbes now face a daunting task of holding such cycles in balan... ver más

31/08/2022

uni.lu

178K€

Presupuesto del proyecto: 178K€

Líder del proyecto

UNIVERSITE DU LUXEMBOURG No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-08-31

MSCA-IF-2019: Individual Fellowships

I+D

Cerrada hace 5 años

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Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

1 Participantes

uni.lu

178.32K€ | Lider

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Duración del proyecto: 29 meses Fecha Inicio: 2020-03-26
Fecha Fin: 2022-08-31

Líder del proyecto

UNIVERSITE DU LUXEMBOURG No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 178K€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Aquatic microbes - both marine and freshwater - drive global biogeochemical cycles. However, owing to the influx of microplastics (MPs) in their natural ecosystems, microbes now face a daunting task of holding such cycles in balance. From passive encounters with suspended particles to active interactions among species, microbes tackle a myriad of environmental signals along the water depths. Crucially, a steady inflow of MPs into aquatic ecosystems has led to reduced species fitness, altered feeding dynamics, and ultimately, ecosystem restructuring. Due to their abundance, durability, and an easy mobility across trophic levels, MPs have been implicated in perturbing diverse aquatic settings. Despite the growing evidence of potentially deleterious ramifications, we still lack a mechanistic understanding of the microbe-MP interactions. BIOMIMIC will zoom into the microscale biophysics mediating the microbe-MP interactions, and develop a mechano-genetic framework to assess the emergent physiological consequences. By combining microfluidics, quantitative imaging, and molecular techniques, I will experimentally simulate, analyse and quantify the impact of MPs on aquatic microbes. To capture ecologically relevant settings, a representative group of bacteria and algal populations will be exposed to MPs with characteristic physico-chemical makeup, over a range of concentrations, and under different hydrodynamic regimes. Specifically, I will uncover MP-induced microbial response: behaviour, physiology, and bio-molecular, and concomitantly, the modification of MP-attributes due to microbial interactions. By cataloging the species-MP encounters in realistic settings, BIOMIMIC will unravel fundamental biophysical principles of microbial response to MPs. Through it's innovative approach, BIOMIMIC, for the first time, will offer a unique framework linking behaviour, physiology and bio-molecular response to MPs, paving the way for potential remediation of this global challenge.

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