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Artificial Intelligence Driven Design of Resorbable Implants

In recent years, the importance of biomedical implants has surged in addressing various medical conditions, including bone fractures, heart ailments, and other healthcare challenges. As healthcare complexities continue to escalate... ver más

15/09/2026

FZU

166K€

Presupuesto del proyecto: 166K€

Líder del proyecto

FYZIKALNI USTAV AV CR V.V.I No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-04-19

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

HORIZON-MSCA-2023-PF-01-01: MSCA Postdoctoral Fellowships 2023

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166.28K€ | Lider

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30-11-2024: Cataluña Gestión For... Se ha cerrado la línea de ayuda pública: Gestión Forestal Sostenible para Inversiones Forestales Productivas para el organismo:

29-11-2024: IDAE En las últimas 48 horas el Organismo IDAE ha otorgado 4 concesiones

29-11-2024: ECE En las últimas 48 horas el Organismo ECE ha otorgado 2 concesiones

Duración del proyecto: 28 meses Fecha Inicio: 2024-04-19
Fecha Fin: 2026-09-15

Líder del proyecto

FYZIKALNI USTAV AV CR V.V.I

TRL 4-5

Presupuesto del proyecto 166K€

Descripción del proyecto In recent years, the importance of biomedical implants has surged in addressing various medical conditions, including bone fractures, heart ailments, and other healthcare challenges. As healthcare complexities continue to escalate, there is a growing demand for biodegradable implants. Pioneering research in medical science is driving the scientific community toward the latest generation of biomedical implants, which closely mimic natural bone and tissues, greatly enhancing their biocompatibility. For instance, temporary medical implants are now based on biodegradable metals like magnesium (Mg), zinc (Zn), and iron (Fe), offering promising potential. Mg alloys, in particular, have a long and illustrious history, especially in bone-support applications. Their elastic modulus closely matches that of natural cortical bone, thereby reducing the occurrence of stress-shielding effects. Furthermore, the body's established pathways for excreting excess Mg via urine make Mg-based alloys ideal candidates for resorbable implants. It is anticipated that Mg-based implants will degrade within a suitable timeframe within the human body. However, there are challenges associated with metallic implants. Firstly, achieving a uniform and predictable degradation rate of implant within the human body. Complete dissolution of the implant after fulfilling its function can provide substantial benefits to the patient by eliminating the risks and costs associated with secondary surgeries and complications, such as hypersensitivity. The second major challenge lies in using biologically safe, low-alloyed magnesium, which, unfortunately, results in high corrosion rates and the formation of hydrogen bubbles that can hinder the healing process. To address these challenges, we propose the development of a novel methodology for producing Mg-based alloys suitable for biodegradable, resorbable implant applications, offering excellent performance.

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