Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

ASVA-CGR

Financiado

Cerrado

Algorithms for Structural Variation Analysis in Challenging Genomic Regions

Structural variations are genomic alterations affecting portions of the chromosomes longer than 50 base pairs. These alterations are a main contributing factor to human diseases and different types of cancer. The main limitation o... ver más

31/08/2026

UK BA

Presupuesto desconocido

Líder del proyecto

UNIVERZITA KOMENSKEHO V BRATISLAVE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-09-01

HORIZON-WIDERA-2023-TALENTS-02-01: ERA Fellowships ExpectedOutcome:This action builds on the MSCA Postdoctoral Fellowships 2023 action (HORIZON-MSCA-PF...

I+D

Cerrada hace 1 año

0% 100%

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

Participantes

UK BA

Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

RYC-2016-20621 Phylogenomic approaches in the sequencing era 309K€ Cerrado

MuG Multi Scale Complex Genomics 3M€ Cerrado

IAGVDHTS Integrated approaches for genomic variation discovery using... 100K€ Cerrado

Humvar Human variation causes patterns and consequences 126K€ Cerrado

BFU2011-28575 NGS-COFFEE: PRODUCCION DE ALINEAMIENTOS GENOMICOS MULTIPLES... 300K€ Cerrado

ARGPHENO Using hidden genealogical structure to study the architectur... 1M€ Cerrado

Duración del proyecto: 23 meses Fecha Inicio: 2024-09-01
Fecha Fin: 2026-08-31

Líder del proyecto

UNIVERZITA KOMENSKEHO V BRATISLAVE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Structural variations are genomic alterations affecting portions of the chromosomes longer than 50 base pairs. These alterations are a main contributing factor to human diseases and different types of cancer. The main limitation of current approaches for the analysis of structural variations lies in their unreliability in characterizing these alterations in repetitive and hard-to-call regions of the genome. Structural variations falling in these regions can not be routinely detected and their significance is still unknown.In this proposal, we aim to develop novel computational approaches to address the challenge of fully characterizing structural variations in these hard and still uninvestigated regions. By developing accurate tools for comprehensive detection of structural variations, we aim to increase our current knowledge of this class of genetic alterations. Moreover, by designing new benchmarking methodologies, we will provide a more accurate evaluation of our as well as other tools. This will also assist the development of new generations of tools able to accurately characterize structural variations that are currently unknown.We will employ a multi-faceted strategy that is not limited to a single sequencing technology. By combining data coming from different sequencing technologies and ideas coming from alignment-based, assembly-based, mapping-free, and pangenomic-based approaches, we will be able to take a significant step towards the complete characterization and analysis of structural variations.The development of new tools and the planned collaboration with biology-oriented research groups will enhance our understanding of the impact of structural variations on human health, diseases, and cancer and hence improve clinical diagnostics and pave the way for personalized medicine.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores