HORIZON EUROPE
Europeo
Scope:Specific challenge: Biocatalysis is increasingly used in synthetic routes to complex molecules. However, the lack of a broad range of reactions platforms catalysed by enzymes and the long development timelines are hindering the full potential of biocatalysis. As a result, while the industry is in need of sustainable routes for a number of important chemical reactions (e.g. some oxidation, C-C bond formation reactions, etc.) biocatalytic alternatives with reduced environmental footprint are still not accessible to large scale chemical synthesis and other industrial conversions.
Scope: Development of specific robust biocatalysts for application at a large scale. Attention should be given to oxidoreductases, oxygenases, lyases. Proposals will have a strong industry drive and include demonstration activities to bridge the gap between lab and industrial scale and to assess the technoeconomic viability of the targeted biotransformation. Proposals should address the design and development of generic platform technologies and methods for fast and accurate enzyme activity determination and enzyme optimization enabling the design of highly efficient biocatalysts with an ex...
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Scope:Specific challenge: Biocatalysis is increasingly used in synthetic routes to complex molecules. However, the lack of a broad range of reactions platforms catalysed by enzymes and the long development timelines are hindering the full potential of biocatalysis. As a result, while the industry is in need of sustainable routes for a number of important chemical reactions (e.g. some oxidation, C-C bond formation reactions, etc.) biocatalytic alternatives with reduced environmental footprint are still not accessible to large scale chemical synthesis and other industrial conversions.
Scope: Development of specific robust biocatalysts for application at a large scale. Attention should be given to oxidoreductases, oxygenases, lyases. Proposals will have a strong industry drive and include demonstration activities to bridge the gap between lab and industrial scale and to assess the technoeconomic viability of the targeted biotransformation. Proposals should address the design and development of generic platform technologies and methods for fast and accurate enzyme activity determination and enzyme optimization enabling the design of highly efficient biocatalysts with an expanded range of substrates and for industrially important conversions. The development of methods for formulation and immobilization of enzymes could be considered with view to optimising process efficiency. Strong weight will be put on industrial leadership of the proposals which are aimed at introducing a real innovation focus. Activities will span between Technology Readiness Levels 5 and 7.
For this topic, proposals should include an outline of the initial exploitation and business plans, which will be developed further in the proposal project.
The Commission considers that proposals requesting a contribution from the EU between EUR 6 and 10 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.
Expected impact:
The demonstration of biocatalytic routes to new chemical reactions at large scale will pave the way for a subsequent market replication. The industrial concepts demonstrated should have the potential for a significant economic, societal and environmental benefit.
Enhancing industry's capabilities for design of biocatalysts (e.g. rational, computational) and their fast quantitative evaluation with view to ensuring the worldwide leading position of the EU biocatalysis sector.
Increasing sustainability and competitive-edge of biotech’s concomitant sectors such as chemical, pharmaceutical intermediates, fine chemicals, food additives, cosmetics etc.
Contributing to realising the objectives of industrial and innovation policy, such as the EU Strategy for Key Enabling Technologies.
Type of action: Innovation Actions
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Características del consorcio
:
La ayuda es de ámbito europeo, puede aplicar a esta linea cualquier empresa que forme parte de la Comunidad Europea.
Características del Proyecto
Los costes de personal subvencionables cubren las horas de trabajo efectivo de las personas directamente dedicadas a la ejecución de la acción. Los propietarios de pequeñas y medianas empresas que no perciban salario y otras personas físicas que no perciban salario podrán imputar los costes de personal sobre la base de una escala de costes unitarios
Los otros costes directos se dividen en los siguientes apartados: Viajes, amortizaciones, equipamiento y otros bienes y servicios. Se financia la amortización de equipos, permitiendo incluir la amortización de equipos adquiridos antes del proyecto si se registra durante su ejecución. En el apartado de otros bienes y servicios se incluyen los diferentes bienes y servicios comprados por los beneficiarios a proveedores externos para poder llevar a cabo sus tareas
La subcontratación en ayudas europeas no debe tratarse del core de actividades de I+D del proyecto. El contratista debe ser seleccionado por el beneficiario de acuerdo con el principio de mejor relación calidad-precio bajo las condiciones de transparencia e igualdad (en ningún caso consistirá en solicitar menos de 3 ofertas). En el caso de entidades públicas, para la subcontratación se deberán de seguir las leyes que rijan en el país al que pertenezca el contratante
Características de la financiación
List of countries and applicable rules for funding: described in part A of the General Annexes of the General Work Programme.
Eligibility and admissibility conditions: described in part B and C of the General Annexes of the General Work Programme.
Evaluation
3.1 Evaluation criteria and procedure, scoring and threshold: described in part H of the General Annexes of the General Work Programme, with the following exceptions:
For second-stage evaluations, the threshold for the criteria Excellence and Impact will be 4. The overall threshold, applying to the sum of the three individual scores, will be 12.
In case of equal overall scores in the ranked list, the priority order of proposals will be established in accordance with part H of the General Annexes, except that proposals will be ranked on the basis of individual scores for the Impact criterion before the Excellence criterion.
3.2 Guide to the submission and evaluation process
Proposal page limits and layout: Please refer to Part B of the standard proposal template.
Indicative timetable for evaluation and grant agreement:
Information on the outcome of two-stage evaluation: maximum 5 months from the final date for submission.
Signature of grant agreements: maximum 3 months from the date of info... Please read carefully all provisions below before the preparation of your application.
List of countries and applicable rules for funding: described in part A of the General Annexes of the General Work Programme.
Eligibility and admissibility conditions: described in part B and C of the General Annexes of the General Work Programme.
Evaluation
3.1 Evaluation criteria and procedure, scoring and threshold: described in part H of the General Annexes of the General Work Programme, with the following exceptions:
For second-stage evaluations, the threshold for the criteria Excellence and Impact will be 4. The overall threshold, applying to the sum of the three individual scores, will be 12.
In case of equal overall scores in the ranked list, the priority order of proposals will be established in accordance with part H of the General Annexes, except that proposals will be ranked on the basis of individual scores for the Impact criterion before the Excellence criterion.
3.2 Guide to the submission and evaluation process
Proposal page limits and layout: Please refer to Part B of the standard proposal template.
Indicative timetable for evaluation and grant agreement:
Information on the outcome of two-stage evaluation: maximum 5 months from the final date for submission.
Signature of grant agreements: maximum 3 months from the date of informing successful applicants.
Provisions, proposal templates and evaluation forms for the type(s) of action(s) under this topic:
Innovation Action:
Specific provisions and funding rates
Standard proposal template
Standard evaluation form
Annotated Model Grant Agreement
Additional provisions:
Horizon 2020 budget flexibility
Classified information
Technology readiness levels (TRL) – where a topic description refers to TRL, these definitions apply.
Financial support to Third Parties – where a topic description foresees financial support to Third Parties, these provisions apply.
Open access must be granted to all scientific publications resulting from Horizon 2020 actions, and proposals must refer to measures envisaged. Where relevant, proposals should also provide information on how the participants will manage the research data generated and/or collected during the project, such as details on what types of data the project will generate, whether and how this data will be exploited or made accessible for verification and re-use, and how it will be curated and preserved.
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