HORIZON EUROPE
European
Scope:Specific challenge: Risk assessment has long been the tool for science-based decision-making and has become an integral part of EU policy development. With regard to chemical hazards, there is increasing concern over the possible ‘cocktail effects’ of combined exposure to multiple food related toxic substances. The complex toxicology of chemical mixtures, and the diversity of the routes of exposure, call for the development of a more mechanism-based and quantitative framework for risk assessment estimating the impact on health, thereby increasing the efficiency and effectiveness of safety evaluations.
Scope: The state-of-the-art frameworks already in place at international level should be reviewed in the quest for a harmonised, evidence- and risk-based approach. Proposals should focus on the health risks of combined exposures to multiple chemicals from multiple sources across differing life stages, while weighing the risks from chemical mixtures in diets against the health benefits from the same foods and taking into account also the gender dimension. New strategies should be developed, implemented and supported by the respectively developed software and database...
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Scope:Specific challenge: Risk assessment has long been the tool for science-based decision-making and has become an integral part of EU policy development. With regard to chemical hazards, there is increasing concern over the possible ‘cocktail effects’ of combined exposure to multiple food related toxic substances. The complex toxicology of chemical mixtures, and the diversity of the routes of exposure, call for the development of a more mechanism-based and quantitative framework for risk assessment estimating the impact on health, thereby increasing the efficiency and effectiveness of safety evaluations.
Scope: The state-of-the-art frameworks already in place at international level should be reviewed in the quest for a harmonised, evidence- and risk-based approach. Proposals should focus on the health risks of combined exposures to multiple chemicals from multiple sources across differing life stages, while weighing the risks from chemical mixtures in diets against the health benefits from the same foods and taking into account also the gender dimension. New strategies should be developed, implemented and supported by the respectively developed software and databases and tested in operational environments – using, for example, ‘omics’ technologies, bioassay systems, mathematical modelling, quantitative structure-activity relationship models and threshold of toxicological concern – so that tiered approaches for testing can be followed and targeted testing protocols developed. Proposals should address responsible research and innovation aspects by developing strategies that will result in a reduction in the use of animals in toxicological research.
The Commission considers that proposals requesting a contribution from the EU in the range of EUR 8 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.
Expected impact:
New strategies that help boost innovation in both the public and private sectors and significantly improve the robustness and efficiency of risk assessment
Improvement in public health through a reduction in food-related toxic substances
Free access for public authorities to the new software and databases developed beyond the lifetime of the projects
A reduction in the use of animals in toxicological research
Support to EU, Codex Alimentarius, and WHO health and food safety policies through the development of new risk assessment strategies
Type of action: Research and innovation actions
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Consortium characteristics
:
The aid is European, you can apply to this line any company that is part of the European Community.
characteristics of the Proyecto
Los costes de personal subvencionables cubren las horas de trabajo efectivo de las personas directamente dedicadas a la ejecución de la acción. Los propietarios de pequeñas y medianas empresas que no perciban salario y otras personas físicas que no perciban salario podrán imputar los costes de personal sobre la base de una escala de costes unitarios
Los otros costes directos se dividen en los siguientes apartados: Viajes, amortizaciones, equipamiento y otros bienes y servicios. Se financia la amortización de equipos, permitiendo incluir la amortización de equipos adquiridos antes del proyecto si se registra durante su ejecución. En el apartado de otros bienes y servicios se incluyen los diferentes bienes y servicios comprados por los beneficiarios a proveedores externos para poder llevar a cabo sus tareas
La subcontratación en ayudas europeas no debe tratarse del core de actividades de I+D del proyecto. El contratista debe ser seleccionado por el beneficiario de acuerdo con el principio de mejor relación calidad-precio bajo las condiciones de transparencia e igualdad (en ningún caso consistirá en solicitar menos de 3 ofertas). En el caso de entidades públicas, para la subcontratación se deberán de seguir las leyes que rijan en el país al que pertenezca el contratante
Characteristics of financing
List of countries and applicable rules for funding: described in part A of the General Annexes of the General Work Programme.
Eligibility and admissibility conditions: described in part B and C of the General Annexes of the General Work Programme.
Evaluation
3.1 Evaluation criteria and procedure, scoring and threshold: described in part H of the General Annexes of the General Work Programme.
3.2 Guide to the submission and evaluation process
Proposal page limits and layout: Please refer to Part B of the standard proposal template.
Indicative timetable for evaluation and grant agreement:
Information on the outcome of one-stage evaluation: maximum 5 months from the final date for submission.
Signature of grant agreements: maximum 3 months from the date of informing successful applicants.
Information on the outcome of two-stage evaluation: maximum 5 months from the final date for submission.
Signature of grant agreements: maximum 3 months from the date of informing successful applicants.
Provisions, proposal templates and evaluation forms for the type(s) of action(s) under this topic:
Research and Innovation Action:
Specific provisions and funding rates
Standard proposal template (administrat... Please read carefully all provisions below before the preparation of your application.
List of countries and applicable rules for funding: described in part A of the General Annexes of the General Work Programme.
Eligibility and admissibility conditions: described in part B and C of the General Annexes of the General Work Programme.
Evaluation
3.1 Evaluation criteria and procedure, scoring and threshold: described in part H of the General Annexes of the General Work Programme.
3.2 Guide to the submission and evaluation process
Proposal page limits and layout: Please refer to Part B of the standard proposal template.
Indicative timetable for evaluation and grant agreement:
Information on the outcome of one-stage evaluation: maximum 5 months from the final date for submission.
Signature of grant agreements: maximum 3 months from the date of informing successful applicants.
Information on the outcome of two-stage evaluation: maximum 5 months from the final date for submission.
Signature of grant agreements: maximum 3 months from the date of informing successful applicants.
Provisions, proposal templates and evaluation forms for the type(s) of action(s) under this topic:
Research and Innovation Action:
Specific provisions and funding rates
Standard proposal template (administrative forms and structure of technical annex)
Standard evaluation form
Annotated Model Grant Agreement
Additional provisions:
Horizon 2020 budget flexibility
Classified information
Technology readiness levels (TRL) – where a topic description refers to TRL, these definitions apply.
Financial support to Third Parties – where a topic description foresees financial support to Third Parties, these provisions apply.
Open access must be granted to all scientific publications resulting from Horizon 2020 actions, and proposals must refer to measures envisaged. Where relevant, proposals should also provide information on how the participants will manage the research data generated and/or collected during the project, such as details on what types of data the project will generate, whether and how this data will be exploited or made accessible for verification and re-use, and how it will be curated and preserved.
Additional information about the call
other advantages
