HORIZON EUROPE
Europeo
Specific Challenge:Vaccines are one of the most important medical breakthroughs in the last 100 years. Every year vaccines save millions of people around the world from illness, disability and death, and they continue to be one of the most cost-effective ways to increase the health and wellbeing of their citizens. Despite this, vaccination uptake faces significant challenges across Europe, and these have increased in particular over the past 20 years. Recent studies have shown Europe to be the world region with the most negative views towards the safety and effectiveness of vaccines, and the importance of childhood vaccination[1].
Recent figures on collected by the World Health Organization (WHO) show that in 2016 only one vaccine had a coverage rate of over 95% in Europe.[2] Seasonal influenza vaccination also remains significantly below the 75% coverage target for older age groups.[3]
Thus, coverage for many vaccines is below the recommended limit. Due to the low vaccine coverage rates, several EU Member States have faced considerable outbreaks of vaccine-preventable diseases in recent years. For example, more than 14,000 cases of measles were reported a...
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Specific Challenge:Vaccines are one of the most important medical breakthroughs in the last 100 years. Every year vaccines save millions of people around the world from illness, disability and death, and they continue to be one of the most cost-effective ways to increase the health and wellbeing of their citizens. Despite this, vaccination uptake faces significant challenges across Europe, and these have increased in particular over the past 20 years. Recent studies have shown Europe to be the world region with the most negative views towards the safety and effectiveness of vaccines, and the importance of childhood vaccination[1].
Recent figures on collected by the World Health Organization (WHO) show that in 2016 only one vaccine had a coverage rate of over 95% in Europe.[2] Seasonal influenza vaccination also remains significantly below the 75% coverage target for older age groups.[3]
Thus, coverage for many vaccines is below the recommended limit. Due to the low vaccine coverage rates, several EU Member States have faced considerable outbreaks of vaccine-preventable diseases in recent years. For example, more than 14,000 cases of measles were reported across the EU in 2017[4], which is more than three times the number of cases reported in 2016. During the same period 50 people in the EU died due to measles[5].
These figures highlight the urgent need to get to grips with vaccine uptake issues, whether uptake of existing or new vaccines. Research has an essential role to play in understanding the underlying causes of poor vaccine uptake, including vaccine hesitancy, and to develop strategies and guidelines to help Member States and Associated countries increase vaccination coverage. A detailed understanding of the obstacles to, and drivers of, vaccination uptake in various settings is necessary to provide appropriate recommendations.
Scope:Proposals should work to increase understanding of the determinants of low vaccine uptake in specific contexts situated in the EU and/or Associated Countries (AC) , and should develop strategies to increase vaccination rates of essential vaccines within these contexts. From this work, proposals should aim to develop a series of recommendations that national and regional public health authorities in the EU and/or Associated Countries could implement in order to increase vaccine coverage. Proposals should build on existing research, findings and available information in this domain, as well as existing guidelines and recommendations from public health authorities, including those from the European Centre for Disease Prevention and Control and WHO/Europe (such as ECDC reports and guidance on vaccine coverage and hesitancy[6], "WHO/SAGE Working Group on Vaccine Hesitancy"[7], WHO/Europe "Guide to tailoring immunization programmes (TIP)"[8].
The approach taken should include a detailed examination of the causes of reduced vaccine uptake, and the design and testing of one or more interventions to improve vaccine uptake. Factors influencing vaccine uptake such as access, inequality, social/cultural influences and vaccine/vaccination-specific issues in specific population(s) that are identified as having lower than average vaccination coverage should be examined. Interventions to improve vaccine uptake should be based on existing high-quality research findings, with a sound hypothesis for why the chosen intervention(s) could be effective at increasing vaccine coverage in the target population(s). These interventions could be made in a wide variety of ways, for example content and style of online or offline media, educational material, modification of primary healthcare practices, access to vaccination, incentivisation, or any other strategies that are supported by a strong hypothesis. Also, the proposals should include a strategy for measuring the impact/success of the proposed interventions.
Finally, the findings of the project will be gathered into a clear and coherent set of recommendations that can be readily utilised by public health authorities in Europe to improve vaccine coverage. Proposals should include in their work the development of a strategy to ensure the implementation of these guidelines.
Proposals should take into account the specific contexts of the population(s) that they are studying, including factors such as age, sex/gender, religion, politics, geography, and socio-economic situation. Proposals should include partners from social science and public health-related disciplines. Proposals will also be expected to create links with other existing initiatives, both in Europe and internationally. This should include specific budget for networking, travelling to or organising meetings for researchers and other stakeholders that work on vaccine uptake challenges.
The Commission considers that proposals requesting a contribution from the EU of between EUR 2 and 3 million would allow this specific challenge to be addressed appropriately. Nonetheless, this does not preclude submission and selection of proposals requesting other amounts.
Expected Impact:Contribute to increasing vaccine coverage in Europe, in particular in specific populations with low vaccine uptake and in specific contexts.Develop practical and readily implementable guidelines to aid national and regional public health authorities in the EU and Associated Countries to increase vaccination rates.Work towards meeting the goals on vaccination set out in President Juncker’s State of the Union address in September 2017[9], the EC Communication on strengthened cooperation against vaccine preventable disease (COM/2018/245)[10] and the Council Recommendation on strengthened cooperation against vaccine preventable diseases)[11].
Cross-cutting Priorities:Socio-economic science and humanitiesOpen ScienceGender
[1]http://www.ebiomedicine.com/article/S2352-3964(16)30398-X/fulltext
[2]http://www.who.int/immunization/monitoring_surveillance/data/gs_eurprofile.pdf
[3]http://ecdc.europa.eu/en/publications/Publications/Seasonal-influenza-vaccination-antiviral-use-europe.pdf
[4]https://ecdc.europa.eu/sites/portal/files/documents/Monthly%20measles%20and%20rubella%20monitoring%20report%20-%20JAN%202018.pdf
[5]https://ecdc.europa.eu/en/news-events/measles-cases-eu-treble-2017-outbreaks-still-ongoing
[6]https://ecdc.europa.eu/en/immunisation-vaccines/vaccine-hesitancy
[7]http://www.who.int/immunization/programmes_systems/vaccine_hesitancy/en/
[8]http://www.euro.who.int/en/health-topics/communicable-diseases/poliomyelitis/publications/2013/guide-to-tailoring-immunization-programmes
[9]http://europa.eu/rapid/press-release_SPEECH-17-3165_en.htm
[10]https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=COM%3A2018%3A245%3AFIN
[11]http://data.consilium.europa.eu/doc/document/ST-14152-2018-REV-1/en/pdf
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Características del consorcio
:
La ayuda es de ámbito europeo, puede aplicar a esta linea cualquier empresa que forme parte de la Comunidad Europea.
Características del Proyecto
Los costes de personal subvencionables cubren las horas de trabajo efectivo de las personas directamente dedicadas a la ejecución de la acción. Los propietarios de pequeñas y medianas empresas que no perciban salario y otras personas físicas que no perciban salario podrán imputar los costes de personal sobre la base de una escala de costes unitarios
Los otros costes directos se dividen en los siguientes apartados: Viajes, amortizaciones, equipamiento y otros bienes y servicios. Se financia la amortización de equipos, permitiendo incluir la amortización de equipos adquiridos antes del proyecto si se registra durante su ejecución. En el apartado de otros bienes y servicios se incluyen los diferentes bienes y servicios comprados por los beneficiarios a proveedores externos para poder llevar a cabo sus tareas
La subcontratación en ayudas europeas no debe tratarse del core de actividades de I+D del proyecto. El contratista debe ser seleccionado por el beneficiario de acuerdo con el principio de mejor relación calidad-precio bajo las condiciones de transparencia e igualdad (en ningún caso consistirá en solicitar menos de 3 ofertas). En el caso de entidades públicas, para la subcontratación se deberán de seguir las leyes que rijan en el país al que pertenezca el contratante
Características de la financiación
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon 2020 projects. See the information in the Online Manual.
In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding to support its participation in projects supported under this topic.
2. Eligibility and admissibility conditions: described in Annex B and Annex C of the Work Programme.
Proposal page limits and layout: please refer to Part B of the proposal template in the submission system below.
3. Evaluation:
Evaluation criteria, scoring and thresholds are described in Annex H of the Work Programme.
Submission and evaluation processes are described in the Online Manual.
The thresholds for each criterion in a single stage process will be 4 (Excellence), 4 (Impact) and 3 (Implementation). The cumulative threshold will be 12.
4. Indicative time for evaluation and grant agreements:
Information on the outcome of evaluation (single-stage call): maximum 5 months from the deadline for submission.
Signature of grant agreements: maximum 8 months from the deadline for submission.
A number of non-EU/non-Associated Countries that are not automatically eligible for funding have made specific provisions for making funding available for their participants in Horizon 2020 projects. See the information in the Online Manual.
In recognition of the opening of the US National Institutes of Health’s programmes to European researchers, any legal entity established in the United States of America is eligible to receive Union funding to support its participation in projects supported under this topic.
2. Eligibility and admissibility conditions: described in Annex B and Annex C of the Work Programme.
Proposal page limits and layout: please refer to Part B of the proposal template in the submission system below.
3. Evaluation:
Evaluation criteria, scoring and thresholds are described in Annex H of the Work Programme.
Submission and evaluation processes are described in the Online Manual.
The thresholds for each criterion in a single stage process will be 4 (Excellence), 4 (Impact) and 3 (Implementation). The cumulative threshold will be 12.
4. Indicative time for evaluation and grant agreements:
Information on the outcome of evaluation (single-stage call): maximum 5 months from the deadline for submission.
Signature of grant agreements: maximum 8 months from the deadline for submission.
5. Proposal templates, evaluation forms and model grant agreements (MGA):
Research and Innovation Action:
Specific provisions and funding rates
Standard proposal template
Standard evaluation form
General MGA - Multi-Beneficiary
Annotated Grant Agreement
Essential information for clinical studies
6. Additional provisions:
Horizon 2020 budget flexibility
Classified information
Technology readiness levels (TRL) – where a topic description refers to TRL, these definitions apply.
Members of consortium are required to conclude a consortium agreement, in principle prior to the signature of the grant agreement.
8. Additional documents:
Introduction WP 2018-20
Health, demographic change and well-being WP 2018-20
General annexes to the Work Programme 2018-2020
Legal basis: Horizon 2020 Regulation of Establishment
Legal basis: Horizon 2020 Rules for Participation
Legal basis: Horizon 2020 Specific Programme
7. Open access must be granted to all scientific publications resulting from Horizon 2020 actions.
Where relevant, proposals should also provide information on how the participants will manage the research data generated and/or collected during the project, such as details on what types of data the project will generate, whether and how this data will be exploited or made accessible for verification and re-use, and how it will be curated and preserved.
Open access to research data
The Open Research Data Pilot has been extended to cover all Horizon 2020 topics for which the submission is opened on 26 July 2016 or later. Projects funded under this topic will therefore by default provide open access to the research data they generate, except if they decide to opt-out under the conditions described in Annex L of the Work Programme. Projects can opt-out at any stage, that is both before and after the grant signature.
Note that the evaluation phase proposals will not be evaluated more favourably because they plan to open or share their data, and will not be penalised for opting out.
Open research data sharing applies to the data needed to validate the results presented in scientific publications. Additionally, projects can choose to make other data available open access and need to describe their approach in a Data Management Plan.
Projects need to create a Data Management Plan (DMP), except if they opt-out of making their research data open access. A first version of the DMP must be provided as an early deliverable within six months of the project and should be updated during the project as appropriate. The Commission already provides guidance documents, including a template for DMPs. See the Online Manual.
Eligibility of costs: costs related to data management and data sharing are eligible for reimbursement during the project duration.
The legal requirements for projects participating in this pilot are in the article 29.3 of the Model Grant Agreement.
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