H2020
Europeo
ExpectedOutcome:Projects are expected to contribute to several of the following expected outcomes:
support to planning and decision making at the national level (e.g. funding bodies, governments) and at European level (e.g. ESFRI) through a sound science case, including expected scientific breakthrough, a gap analysis and a feasibility/design study for a future research infrastructure to manage, integrate and sustain large medical cohort studies;ensuring stewardship and long-term availability of data and samples related to existing and future large medical cohort studies for their re-use for secondary research;strengthening and integration of existing capacities in the field;new services and access opportunities available to the research community, allowing to better tackle medical challenges.
Scope:This topic aims at supporting the development of new concepts for a research infrastructure at European level, to manage, integrate and sustain large medical cohort studies. The possibility to extend the scope of already existing infrastructures and/or integrate in a sustainable way existing pan-European and national capacities to cover this need and provide RI servi...
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ExpectedOutcome:Projects are expected to contribute to several of the following expected outcomes:
support to planning and decision making at the national level (e.g. funding bodies, governments) and at European level (e.g. ESFRI) through a sound science case, including expected scientific breakthrough, a gap analysis and a feasibility/design study for a future research infrastructure to manage, integrate and sustain large medical cohort studies;ensuring stewardship and long-term availability of data and samples related to existing and future large medical cohort studies for their re-use for secondary research;strengthening and integration of existing capacities in the field;new services and access opportunities available to the research community, allowing to better tackle medical challenges.
Scope:This topic aims at supporting the development of new concepts for a research infrastructure at European level, to manage, integrate and sustain large medical cohort studies. The possibility to extend the scope of already existing infrastructures and/or integrate in a sustainable way existing pan-European and national capacities to cover this need and provide RI services for large medical cohort studies should be assessed as a first option, identifying what is missing and the necessary new developments. Such an infrastructure will also enable an appropriate exploitation of past investments by EU framework programmes or other European funders on the development of medical cohorts.
The numerous and diverse medical cohort studies in Europe, initiated at Member States level or in the context of EU-funded projects, require major resource investments to be set up, mature and serve multiple research queries over long period of times. The research potential (e.g. statistical power or geographical coverage) of individual cohorts can be scaled up, when similar, sufficiently compatible individual cohorts (e.g. in different EU countries) are harmonized and integrated. A research infrastructure could ensure the needed long term sustainability for cohorts and the technical platform for data integration across cohorts as well as a properly implemented data access governance. Proposals for the new RI concept development will tackle all key questions concerning the technical and conceptual feasibility of an effective RI service offer, at EU level, to manage, integrate and sustain large medical cohort studies.
In this respect, proposals should address all following aspects:
demonstrate relevance in relation to ERA, including to the existing landscape, and the advancement with respect to the state-of-art of the new sustainable integrated service or infrastructure;highlight the research challenges the new sustainable integrated service or research infrastructure will make possible to address, including at global level;indicate the gaps in the research infrastructure landscape it will cover and the synergies with other existing infrastructures at European and global level, including those co-financed from other EU instruments (e.g.: Cohesion policy);indicate, when relevant, the potential impact of this research infrastructure at regional level. Proposals should also convincingly demonstrate that the project will effectively:
identify suitable IT technologies and the architecture (e.g. single site or distributed, …) for the research infrastructure;identify scientific user communities (and their related needs) that will benefit from access to RI services, including scientific data and instrumentation, and plan the research services to be offered to users;assess and identify suitable governance models and implement strategies for institutional/stakeholders’ commitment and engagement;develop initial financial plans for the implementation and operation of the infrastructure as well as preliminary ideas for long-term sustainability, including synergies with other funds and programmes (e.g.: ERDF);develop plans for an efficient data curation and preservation and for the provision of GDPR compliant access to data managed by the infrastructure, in line with the FAIR principles to the extent possible. Projects could pilot the harmonization of a limited number of European strategic cohorts, that are sustained in the long-term for generating evidence in a given field, aiming at integrating their respective data sets so as to enable cross-cohort queries. Synergies with successful proposals under the HORIZON-HLTH-2023-DISEASE-03-05[1] topic should be sought.
When relevant, environmental (including climate-related) impacts and the optimisation of resource and energy use, as well as the gender dimension of cohort studies, should be integrated in the concept development of the new research infrastructures.
[1]Pandemic preparedness and response: Sustaining established coordination mechanisms for European adaptive platform trial network and cohort network
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La ayuda es de ámbito europeo, puede aplicar a esta linea cualquier empresa que forme parte de la Comunidad Europea.
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Para el presupuesto subvencionable la intensidad de la ayuda en formato fondo perdido podrá alcanzar como minimo un 100%.
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