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West-Life

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Cerrado

World wide E infrastructure for structural biology

The focus of structural biology is shifting from single macromolecules produced by simpler prokaryotic organisms, to the macromolecular machinery of higher organisms, including systems of central relevance for human health. Struct... ver más

31/10/2018

UKRI

4M€

Presupuesto del proyecto: 4M€

Líder del proyecto

UNITED KINGDOM RESEARCH AND INNOVATION No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 10 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2018-10-31

EINFRA-9-2015: e-Infrastructures for virtual resea... Scope:Specific challenge: There is yet considerable potential and room for development in the use of...

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

10 Participantes

UKRI

780.75K€ | Lider

INFN

344.00K€ | Participante

393.25K€ | Participante

EMBL

641.75K€ | Participante

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Duración del proyecto: 39 meses Fecha Inicio: 2015-07-28
Fecha Fin: 2018-10-31

Líder del proyecto

UNITED KINGDOM RESEARCH AND INNOVATION No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 4M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto The focus of structural biology is shifting from single macromolecules produced by simpler prokaryotic organisms, to the macromolecular machinery of higher organisms, including systems of central relevance for human health. Structural biologists are expert in one or more techniques. They now often need to use complementary techniques in which they are less expert. Instruct supports them in using multiple experimental techniques, and visiting multiple experimental facilities, within a single project. The Protein Data Bank is a public repository for the final structure. Journals require deposition as a precondition of publication. However, metadata is often incomplete. This project will pilot an infrastructure for storing and processing data that supports the growing use of combined techniques. There are some technique-specific pipelines for data analysis and structure determination. Little is available in terms of automated pipelines to handle integrated datasets. Integrated management of structural biology data from different techniques is lacking altogether. The proposed activity will integrate the data management facilities that already exist, and enable the provision of new ones. The resulting integration will provide users with an overview of the experiments performed at the different research infrastructures visited, and links to the different data stores. It will extend existing facilities for processing this data. As processing is performed, it will automatically capture metadata reflecting the history of the project. The effort will use existing metadata standards, and integrate with them new domain-specific metadata terms. This proposal will develop application level service specific to uses cases in structural biology, enabling structural biologists to get the benefit of the generic services developed by EUDAT and the EGI.

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