Innovating Works

HUMO

Financiado
What is everybody doing? Social prediction categorization and monitoring in th...
What is everybody doing? Social prediction categorization and monitoring in the Prefrontal Cortex of the Macaque adopting a new human monkey H M interactive paradigm. Primates live in a complex social environment, in which they need to maintain track of their past social interactions and learn to formulate prediction on what specific groupmates are likely to do based on their past experiences.... Primates live in a complex social environment, in which they need to maintain track of their past social interactions and learn to formulate prediction on what specific groupmates are likely to do based on their past experiences. I have previously contributed to show that the PF (prefrontal cortex) has a main function in the generation of goals based on the current contexts and events, but its role in social cognition is still little explored. In this context, the frontal Pole cortex (FPC) has been associated to mentalizing functions and there is a link between the autism spectrum disorder and its abnormalities. However until recently, no one has been able to record neural activity from FPC, but us. I propose to investigate the role of the monitoring function of FPC in association to the dorsolateral (PFD) and orbitofrontal (OFC) cortex, recording from the entire network up to 256 neurons simultaneously. We have developed the first human-monkeys (H-M) paradigm to test several hypotheses. The task is a non-match-to goal (NMTG) task in which the monkeys are trained to switch from their choice on the previous trial to a different one. In a subset of trials the monkey observe a human partner (either cooperative or uncooperative) performing the task. When the human partner conclude his turn, the monkeys have to switch to a new goal discarding the human’s previous goal. I will explore the role of PFD in social decisions in predicting other agents decisions and distinguishing and categorizing cooperative and uncooperative agents, and the role of OFC in monitoring others’ choices. I expect that PFD will maintain, as it does with past and future goals, separate records for the past choices of different agents while PFO might contribute to solve credit assignment problems also in relationship to other’s behaviors. ver más
31/08/2021
1M€
Duración del proyecto: 68 meses Fecha Inicio: 2015-12-07
Fecha Fin: 2021-08-31

Línea de financiación: concedida

El organismo H2020 notifico la concesión del proyecto el día 2021-08-31
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
ERC-CoG-2014: ERC Consolidator Grant
Cerrada hace 10 años
Presupuesto El presupuesto total del proyecto asciende a 1M€
Líder del proyecto
UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5