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CLASSICA

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VALIDATING AI IN CLASSIFYING CANCER IN REAL-TIME SURGERY

Building on breakthrough research in the AI analysis of fluorescence and perfusion in cancer tissues, this project clinically validates the use of AI-driven imaging and decision support in real-time cancer surgery. Cancer and heal... ver más

30/04/2026

NUID UCD

6M€

Presupuesto del proyecto: 6M€

Líder del proyecto

UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-05-01

HORIZON-HLTH-2021-DISEASE-04-04: Clinical validation of artificial i... ExpectedOutcome:This topic aims at supporting activities that are enabling or contributing to one or...

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NUID UCD

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Duración del proyecto: 47 meses Fecha Inicio: 2022-05-01
Fecha Fin: 2026-04-30

Líder del proyecto

UNIVERSITY COLLEGE DUBLIN NATIONAL UNIVERSITY... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 6M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto Building on breakthrough research in the AI analysis of fluorescence and perfusion in cancer tissues, this project clinically validates the use of AI-driven imaging and decision support in real-time cancer surgery. Cancer and healthy tissue have radically different local blood perfusion patterns. This perfusion can be captured using near-infrared video after systemic fluorophore (indocyanine green) injection. Analysis of the video can digitally identify regions of cancer by tracking the perfusion over the initial seconds after dye administration by comparing the fluorescence signal in these areas with those in adjacent normal tissue within the same endolaparoscopic field of view. Application of AI methods (including computer vision and machine learning techniques) has enabled this differential classification to occur in real time so that better, individualised surgical decisions can be taken during an operation. In this project, we build up our existing AI solution research prototype into an operating room-standard surgical tool and validate its performance, reliability, usability and acceptance in five leading cancer surgery centres across Europe (500 patients). The validation studies address (a) generalisability across clinics; (b) biopsy and tumour identification; and (c) optimised resection of large (>3cm) rectal polyps, a key area of current surgical practice where the biggest clinical challenge ensuring accurate patient selection for curative therapy. Training and education, communication and dissemination will be delivered by IRCAD, Europe's leading surgical education organisation. Legal, regulatory and liability research (co-led by UCPH CeBIL Centre and PSU) and usability and acceptance research (led by surgical professional organisation EAES) will identify and address all obstacles to widespread use of this technology in particular, and of real-time AI in the operating-room in general. Draft clinical guidelines will be created for future EAES adoption.

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