Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

RESTORE

Financiado

User centred smart nanobiomaterial based 3D matrices for chondral repair

The RESTORE project aims at developing an effective approach to manage the specific unmet clinical needs to treat knee chondral lesions. RESTORE, built upon the consortium’s proofs-of-concept and discussions between orthopaedic su... ver más

31/08/2022

INEB

6M€

Presupuesto del proyecto: 6M€

Líder del proyecto

INEBINSTITUTO NACIONAL DE ENGENHARIA BIOMEDIC... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Ver 13 Participantes

Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2022-08-31

NMBP-22-2018: Osteoarticular tissues regeneration...

I+D

Cerrada hace 6 años

0% 100% 100%

13 Participantes

INEB

933.24K€ | Lider

NVISION INTERACTIVE TECHNOLO...

VGR

553.05K€ | Participante

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

CTQ2016-76721-R NUEVAS ESTRUCTURAS 3D BASADAS EN NANOCOMPOSITES DE NANOMATER... 200K€ Cerrado

PACMAN sPatially and environmentAlly aCtuable nancoMposite hydrogel... 173K€ Cerrado

PTQ-08-03-07879 Desarrollo de un grupo de investigación en el area de la nan... 83K€ Cerrado

PCIN-2015-261 NANOCOMPOSITES JERARQUICOS DOPADOS IONICAMENTE COMO SOPORTES... 110K€ Cerrado

NANOREMEDI Functional Nano-Scaffolds for Regenerative Medicine 3M€ Cerrado

PID2020-120202RB-I00 NANOMATERIALES INNOVADORES REGENERATIVOS 145K€ Cerrado

Duración del proyecto: 44 meses Fecha Inicio: 2018-12-12
Fecha Fin: 2022-08-31

Líder del proyecto

INEBINSTITUTO NACIONAL DE ENGENHARIA BIOMEDIC... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 6M€

Descripción del proyecto The RESTORE project aims at developing an effective approach to manage the specific unmet clinical needs to treat knee chondral lesions. RESTORE, built upon the consortium’s proofs-of-concept and discussions between orthopaedic surgeons, tissue engineers, material scientists, cell biologists and SMEs, will realize a new generation of smart nanoenabled 3D matrices able to fit into complex lesion geometry, modulate undesirable biological events, and remotely control, stimulate and monitor cartilage repair. To create smart and functional 3D matrices, RESTORE will develop (i) nanobiomaterial-based nanocarriers to modulate inflammatory, cartilage extracellular matrix degradation and infection threats, (ii) stimuli-responsive nanobiomaterials tuned via external physical stimulus using radiofrequency and electromagnetic fields, and (iii) non-invasive wearable and wireless device for remote stimulus and regeneration monitoring. The nanobiomaterials will be integrated into cutting-edge 3D matrices that meet the needs of severe and mild chondral lesions: 1) the COPLA Scaffold commercialised since 2017 for animal health use and 2) 3D cartilage microtissues engineered via 3D bioprinting of iPS cells in a nanocellulose and alginate bioink. The technology development in RESTORE will reach TRL5 and enable substantial clinical advances in regenerative medicine. Untreated or not-correctly treated chondral lesions are likely to progress towards osteoarthritis (OA), which affects 242 million people globally (costs/patient/year: 10,452€). RESTORE will address the shortfalls of current therapeutic solutions while aiming to reduce the overall burden of OA. RESTORE’s outcomes hold high exploitation and commercial potential to boost the competitiveness of European companies, striving to diminish or delay the onset of OA, reducing hospitalization, number of surgeon interventions and time off work, thus leading to more cost-efficient health care and promote wellbeing and active ageing.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores