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UniPAT

Financiado

Universal Pulses for Parallel Transmission and Magnetic Resonance Imaging

The parallel transmission technology is a promising technique to counteract the radiofrequency (RF) field inhomogeneity problem in Magnetic Resonance Imaging (MRI) at ultra-high field. It consists of placing around the subject sev... ver más

28/02/2018

CEA

150K€

Presupuesto del proyecto: 150K€

Líder del proyecto

COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENER... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

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Financiación concedida El organismo H2020 notifico la concesión del proyecto el día 2018-02-28

Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:

ERC-PoC-2015: ERC Proof of Concept Grant

I+D

Cerrada hace 9 años

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2 Participantes

CEA

149.63K€ | Lider

SOCIEDAD ANONIMA DE PREFORMA...

333.46K€ | Participante

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Duración del proyecto: 19 meses Fecha Inicio: 2016-07-22
Fecha Fin: 2018-02-28

Presupuesto del proyecto 150K€

Descripción del proyecto The parallel transmission technology is a promising technique to counteract the radiofrequency (RF) field inhomogeneity problem in Magnetic Resonance Imaging (MRI) at ultra-high field. It consists of placing around the subject several RF transmitters that can be controlled independently in amplitude and phase. By using sophisticated algorithms, it is then possible to design the respective waveforms which lead to a uniform excitation. This powerful tool on the other hand has remained a research instrument mostly due to the calibration and calculation time necessary to exploit the technology in each exam (around 10 minutes), and the required expertise to calculate the waveforms. In this Proof-of-Concept project, we propose to establish the scientific validity, technical feasibility and market potential of universal RF pulses. The instigator of the project indeed has acquired supporting evidence during his ERC project that it is possible to generate a set of RF pulses predesigned to be robust with respect to patient variability. That way, the so-called universal pulses can be applied to a category of patients without any special calibration or particular expertise. The use of parallel transmission thereby could become accessible to any clinical MRI platform equipped appropriately. Universal pulses would represent a plug and play solution. This Proof-of-Concept project hence will be carried out by first accumulating the data necessary to create a database of RF field maps acquired on different human brains. Through the use of tools developed during the corresponding ERC project, the pulses will be designed to work robustly on the cohort. These pulses will then be blindly applied to a group of new healthy adult volunteers without any particular calibration or calculation. Experiments will be performed at 7T using a commercial RF coil to market the results better and offer a readily implementable product to companies.

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