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STEPUPIORS

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Cerrado

TWINNING FOR A EUROPEAN CONSORTIUM OF RECTAL CANCER RESEARCH INSTITUTIONS THROUG...

TWINNING FOR A EUROPEAN CONSORTIUM OF RECTAL CANCER RESEARCH INSTITUTIONS THROUGH STEPPING UP SCIENTIFIC, TECHNOLOGICAL AND INNOVATION EXCELLENCE OF IORS "Neoadjuvant chemoradiotherapy (CRT) is the gold standard in locally advanced rectal cancer (LARC), but the response is not uniform among patients and improvements are currently being assessed. Profiling the response to CRT in pat... ver más

30/09/2025

INSTITUTE OF ONCOL...

2M€

Presupuesto del proyecto: 2M€

Líder del proyecto

INSTITUT ZA ONKOLOGIJU I RADIOLOGIJU SRBIJE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Fecha límite participación Sin fecha límite de participación.

Ver 5 Participantes

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2022-07-14

HORIZON-WIDERA-2021-ACCESS-03-01: Twinning Expected Outcome:To prevent further disparities, maximize investment in R&D and enhance economic...

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Cerrada hace 3 años

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Este proyecto no cuenta con búsquedas de partenariado abiertas en este momento.

Información adicional privada

No hay información privada compartida para este proyecto. Habla con el coordinador.

5 Participantes

INSTITUTE OF ONCOLOGY AND RA...

750.00K€ | Lider

BIOMEDICAL RESEARCH FOUNDATI...

250.00K€ | Participante

FUNDACIO CLINIC PER A LA REC...

250.00K€ | Participante

NKI AVL

250.00K€ | Participante

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Duración del proyecto: 38 meses Fecha Inicio: 2022-07-14
Fecha Fin: 2025-09-30

Líder del proyecto

INSTITUT ZA ONKOLOGIJU I RADIOLOGIJU SRBIJE No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 2M€

Fecha límite de participación Sin fecha límite de participación.

Descripción del proyecto "Neoadjuvant chemoradiotherapy (CRT) is the gold standard in locally advanced rectal cancer (LARC), but the response is not uniform among patients and improvements are currently being assessed. Profiling the response to CRT in patients with LARC would enable more adequate selection of patients who would benefit most from CRT while minimizing adverse effects and toxicity. Patients with a favorable response to CRT might be candidates for a less invasive surgical approach or for enrollment in a ""watch and wait"" approach in the case of a complete clinical response (cCR). This would increase their quality of life and contribute to the overall reduction of treatment cost. Identification of novel therapeutic targets might also benefit rectal cancer patients who do not respond well to neoadjuvant CRT. The main aim of the STEPUPIORS project is to establish a European consortium of research institutions dedicated to defining prognostic biomarkers in rectal cancer. Specific project objectives that would enable addressing this unmet clinical need are: Objective 1: Determine the molecular profile of response to neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer through a newly formed rectal cancer consortium with complementary expertise Objective 2: Strengthen the research, management and administrative abilities of the Institute for Oncology and Radiology of Serbia (IORS) located in Belgrade, Serbia along with the establishment of a rectal cancer biobank Objective 3: Establish a long-lasting knowledge, personnel, and sample exchange between participating institutions in the rectal cancer consortium. The STEPUPIORS project aligns with Europe’s beating cancer plan and the Horizon Europe strategic plan 2021-2024 within the health cluster, through setting up a research consortium that will enable improvement of rectal cancer prognosis, monitoring and treatment and lead to better health outcomes."

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