Innovating Works

TrojanDC

Financiado
TrojanDC - A BREAKTHROUGH DEEP-TECH INNOVATION FOR CANCER IMMUNOTHERAPY
The Challenge: Cancer remains one of the major challenges to modern medicine affecting one-in-three people in Europe. Available immunotherapies are effective in a limited number of patients and often lose their efficacy due to het... The Challenge: Cancer remains one of the major challenges to modern medicine affecting one-in-three people in Europe. Available immunotherapies are effective in a limited number of patients and often lose their efficacy due to heterogeneity and lack of tumor-antigen presentation. Despite these shortcomings, the global immune-oncology market is one of the fastest growing therapeutics markets. Large players like Merck, Pfizer, and Novartis have shown to be keen on acquisitions of high-potential technologies. There is thus an urgent need and high demand for innovative cost-effective immunotherapies consistently effective in a broader range of cancer patients. The innovation: Asgard Therapeutics is a pre-clinical start-up company developing innovative cancer immunotherapies based in in-vivo cell reprogramming. The company is led by the scientific co-founder and CEO Cristiana Pires who, together with her co-founders, pioneered direct reprogramming to induce antigen-presenting dendritic cells. Asgard raised a € 6M seed round of funding to generate proof-of-concept for its lead candidate TrojanDC, a paradigm-shifting immunotherapy that reprograms cancer cells into antigen-presenting dendritic cells, allowing the presentation of their tumor antigens to the immune system, thereby eliciting potent anti-cancer immunity. TrojanDC has the potential to overcome challenges with current immunotherapies by reinstating cancer immunogenicity. The Women TechEU grant will allow defining a clear roadmap for the IND-enabling studies and FIH clinical trials and creating a comprehensive business plan required to raise Series A funding in Q4 2023. The Impact: With strong proof-of-concept data already obtained, an exceptional team of high-performing scientists and a strong syndicate of seasoned VCs, Asgard Therapeutics is in a unique position to develop first-in-class cancer immunotherapy based in in-vivo reprogramming. ver más
30/06/2024
75K€
Duración del proyecto: 12 meses Fecha Inicio: 2023-06-02
Fecha Fin: 2024-06-30

Línea de financiación: concedida

El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2024-06-30
Línea de financiación objetivo El proyecto se financió a través de la siguiente ayuda:
HORIZON-EIE-2022-SCALEUP-02-02: Women TechEU
Cerrada hace 2 años
Presupuesto El presupuesto total del proyecto asciende a 75K€
Líder del proyecto
ASGARD THERAPEUTICS AB No se ha especificado una descripción o un objeto social para esta compañía.
Perfil tecnológico TRL 4-5