Translating adaptive microscopes to the clinic for tissue analysis during surger...
Translating adaptive microscopes to the clinic for tissue analysis during surgery
Optical microscopes are one of the key tools that that guide a surgeon during the most complicated surgeries and provide the necessary feedback. State-of-the-art confocal laser scanning microscopes and endoscopes provide the most...
ver más
¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video
Proyectos interesantes
UNCM08-1E-023
Equipo para tratamiento de muestras y análisis para microsco...
101K€
Cerrado
UNCM13-1E-2127
Ampliación y mejora de la Unidad de Instrumentación Biomédic...
20K€
Cerrado
THESIS
The Single Optical Fibre Scalpel
195K€
Cerrado
EQC2019-005689-P
Adquisición de un Sistema de Microscopía de Altas Prestacion...
241K€
Cerrado
CSIC10-4E-437
Microscopio de Fluorescencia Motorizado con Sistema Autónomo...
87K€
Cerrado
Fecha límite de participación
Sin fecha límite de participación.
Descripción del proyecto
Optical microscopes are one of the key tools that that guide a surgeon during the most complicated surgeries and provide the necessary feedback. State-of-the-art confocal laser scanning microscopes and endoscopes provide the most reliable images for diagnostic purposes. However, they are not yet capable enough to be used intraoperatively for high-resolution fluorescence imaging in some of the most complicated surgeries. Ideally, the surgeon needs to see the tissue in three dimensions at cellular resolution. In principle, such images can be generated by a confocal fluorescence microscope, but a key obstacle limiting new applications is that these microscopes are prone to the detrimental effects of aberrations. This means that only the upper layers of cells can be seen clearly. We propose a new technology for surgical microscopes that will use adaptive optics to correct for problematic tissue-induced aberrations. Aberration correction will enable deeper penetration with reduced imaging times that are required for real time feedback and sharper cellular level images with better contrast. Adaptive optics has already enabled aberration correction in research microscopes, however such technology is not yet available for use in the clinic. We propose to develop new generation of adaptive optical confocal fluorescence microscopes and endoscopes for intraoperative use in the clinic. The proposed microscope will enable more effective removal of abnormal tissues and reduced surgery times. The resulting shorter and more successful surgery will have manifold benefits to health and quality of life, not to mention economic savings. The new prototype microscopes will form the basis of future commercial development to disseminate this technology widely.