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RUMIGEN

financed

Towards improvement of ruminant breeding through genomic and epigenomic approach...

Towards improvement of ruminant breeding through genomic and epigenomic approaches More sustainable breeding programs and linked technologies need to be in line with social demand and to take into account genetic diversity as well as required adaption to climate change. Towards these aims, RUMIGEN will ensure en... see more

31/05/2026

INRAE

7M€

Project Budget: 7M€

Project leader

INSTITUT NATIONAL DE RECHERCHE POUR LAGRICULT... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

PARTICIPATION DEPralty Sin fecha límite de participación.

Ver 19 Participantes

Financing granted El organismo H2020 notifico la concesión del proyecto The day 2021-05-05

SFS-13-2020: Genome and epigenome enabled breedi... Specific Challenge:Genetics is currently one of the important levers for efficient livestock product...

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19 Participantes

INRAE

1.15M€ | Leader

AGRIC BEMVIG

355.00K€ | participant

DANISH BOARD OF TECHNOLOGY F...

459.08K€ | participant

353.94K€ | participant

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Project duration: 60 months Date Start: 2021-05-05
End date: 2026-05-31

Project leader

INSTITUT NATIONAL DE RECHERCHE POUR LAGRICULT... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Project Budget 7M€

participation deadline Sin fecha límite de participación.

Project description More sustainable breeding programs and linked technologies need to be in line with social demand and to take into account genetic diversity as well as required adaption to climate change. Towards these aims, RUMIGEN will ensure engagement of a variety of stakeholders to assess social perception of breeding objectives and related technologies in ruminants. It will define rooms of acceptance which will be implemented in sustainable breeding scenarios that will then be assessed through multi-actor panels. To define new breeding programs, RUMIGEN, which brings together partners representing pan-European leaders on ruminant breeding, will question trade-offs and pleiotropic effects through adaptation to environmental stressors such as heat stress. Cosmopolitan and local dairy cattle breeds will be analysed evaluating mid to long term effects as well as impact on next generation (fetal programming). This work will rely on large-scale data from commercial farms combined with climatic data, taking advantage of the large panel of situations across Europe and of a unique design involving half-sister cows raised in contrasted conditions, Denmark and India. Diversity will be also studied with new breed genome assemblies. Methods will be developed to account for rare alleles and to maintain diversity. An epigenotyping platform will be designed to (i) explore sperm epigenome influences on bull fertility and progeny, (ii) decipher underlying mechanisms of epigenetic inheritance and (iii) evaluate how much epigenetic biomarkers improve phenotype prediction. RUMIGEN will answer questions on genome editing specificity and safety issues, assessing its potential to preserve genetic diversity and increase genetic gains. Overall, RUMIGEN will develop models combining genomics, epigenomics and biotechnologies to improve genomic selection, preserve genetic biodiversity and avoid genetic load. Improved phenotype prediction will pave the way to new management indexes for precision farming.

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