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To develop a novel class of metalloenzymes for application in novel asymmetric C...
To develop a novel class of metalloenzymes for application in novel asymmetric C H activation chemistry.
Chemical synthesis through the activation of inert C-H bonds allows scientist to efficiently assemble complex organic molecules which have specific function. We aim to develop a novel class of metalloenzymes, where a transition me...
Chemical synthesis through the activation of inert C-H bonds allows scientist to efficiently assemble complex organic molecules which have specific function. We aim to develop a novel class of metalloenzymes, where a transition metal catalyst is embedded into a genetically engineered protein, for rhodium catalysed asymmetric C-H activation reactions. We believe that the approach of incorporating a transition metal into a protein will allow for precise control of the chemical environment around the transition metal, allowing us to control many key outcomes of the chemical reaction such as enantioselectivity, regioselectivity and reaction rates. This technology will allow for the development of C-H activation reactions that have previously been inaccessible to the synthetic chemistry community.
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Duración del proyecto: 35 meses
Fecha Inicio: 2015-04-13
Fecha Fin: 2018-03-31
Fecha Fin: 2018-03-31
Línea de financiación: concedida
El organismo H2020 notifico la concesión del proyecto el día 2018-03-31
Línea de financiación objetivo
El proyecto se financió a través de la siguiente ayuda:
MSCA-IF-2014-GF:
Marie Skłodowska-Curie Individual Fellowships (IF-GF)
Cerrada
hace 10 años
Presupuesto
El presupuesto total del proyecto asciende a
252K€
Líder del proyecto
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UN...
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Perfil tecnológico
TRL
4-5
Perfil tecnológico
TRL
4-5
374.67K€ |
Participante