Hola,
¿eres nuevo aquí?

Regístrate gratis y conecta tu empresa con financiación pública, partners y proyectos.

Tengo cuenta

Regístrate

Ver video

EVOL-SV

Financiado

The role of structural genomic variants in eco-evolutionary processes

Genetic diversity is a fundamental level of biodiversity at a time of global change. It provides variation that underpins species persistence and their adaptation to changing environments. Variation in the direction or presence of... ver más

30/11/2028

CNRS

1M€

Presupuesto del proyecto: 1M€

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Financiación concedida El organismo HORIZON EUROPE notifico la concesión del proyecto el día 2023-10-04

ERC-2023-STG: ERC STARTING GRANTS Scope:Objectives

I+D

Cerrada hace 2 años

0% 100%

1 Participantes

CNRS

1.50M€ | Lider

Conecta tu I+D

¿Tienes un proyecto y buscas un partner? Gracias a nuestro motor inteligente podemos recomendarte los mejores socios y ponerte en contacto con ellos. Te lo explicamos en este video

Proyectos interesantes

PID2021-124501NB-I00 APROXIMACION ECOLOGICA Y GENOMICA A MECANISMOS DE DIVERGENCI... 218K€ Cerrado

PID2020-113168GB-I00 GENOMICA POBLACIONAL DE LA ADAPTACION POLIGENICA EN GRADIENT... 143K€ Cerrado

BFU2010-18477 VARIABILIDAD GENETICA Y GENOMICA EN REGIONES DE MICRORNAS HA... 157K€ Cerrado

PID2019-105312GB-I00 HERRAMIENTAS METAGENOMICAS PARA EL ESTUDIO DE LA BIODIVERSID... 121K€ Cerrado

CNS2023-143604 Biodiversidad 200K€ Cerrado

CGL2008-00378 FILOGENIA Y FILOGEOGRAFIA MOLECULAR DE PLANARIAS TERRESTRES... 143K€ Cerrado

Duración del proyecto: 61 meses Fecha Inicio: 2023-10-04
Fecha Fin: 2028-11-30

Líder del proyecto

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE... No se ha especificado una descripción o un objeto social para esta compañía.

TRL 4-5

Presupuesto del proyecto 1M€

Descripción del proyecto Genetic diversity is a fundamental level of biodiversity at a time of global change. It provides variation that underpins species persistence and their adaptation to changing environments. Variation in the direction or presence of DNA sequences has been largely overlooked until now. Yet, those structural variants (SVs) represent a key aspect of genetic diversity. SVs cover 3 to 10 times more of the genome than the well-studied single-nucleotide variants and have different properties (length, effect on recombination, mutation rate). Structural variation thus represents a quantitative and qualitative shift in our understanding of genetic diversity, with predicted, but understudied, implications for evolution. The project EVOL-SV calls for a reassessment of the genomic basis of eco-evolutionary processes. My ambition is to lead new research avenues on the impact of SVs in ecology and evolution and to determine the contribution of SVs to current biodiversity. I will combine cutting-edge genomics and powerful experimental approaches, developed throughout my career, to perform multidisciplinary research on a focal system, Coelopa flies, and then across taxa. First, I will investigate SVs within a population genetic framework in Coelopa spp. to determine how SV properties affect their distribution and effects on fitness. Second, I will assess the contribution of SVs to deleterious load in a case of range shift northwards. Third, I will examine how SVs contribute to phenotypic adaptation, focusing on parallel climatic gradients and rapid thermal variation. Fourth, at a broader phylogenetic level, I will draw general principles about the evolution of structural genetic diversity. EVOL-SV will have long-term impacts by providing the first comprehensive assessment of structural genetic diversity across the tree of life, developing the study of SVs in non-model species, and determining how genetic architecture contributes to evolutionary response in a rapidly changing world.

Conecta tu I+D

Entra hoy

¿Olvidé mi contraseña?

Financiación

Empresas

CTIs/Universidades

Proyectos

Investigadores